Transmembrane protein 53
1_MASAE 6_ LDYTI 11_ EIPDQ 16_ PCWSQ 21_ KNSPS 26_ PGGKE 31_ AETRQ 36_ PVVIL 41_ LGWGG 46_ CKDKN 51_ LAKYS 56_ AIYHK 61_ RGCIV 66_ IRYTA 71_ PWHMV 76_ FFSES 81_ LGIPS 86_ LRVLA 91_ QKLLE 96_ LLFDY 101_ EIEKE 106_ PLLFH 111_ VFSNG 116_ GVMLY 121_ RYVLE 126_ LLQTR 131_ RFCRL 136_ RVVGT 141_ IFDSA 146_ PGDSN 151_ LVGAL 156_ RALAA 161_ ILERR 166_ AAMLR 171_ LLLLV 176_ AFALV 181_ VVLFH 186_ VLLAP 191_ ITALF 196_ HTHFY 201_ DRLQD 206_ AGSRW 211_ PELYL 216_ YSRAD 221_ EVVLA 226_ RDIER 231_ MVEAR 236_ LARRV 241_ LARSV 246_ DFVSS 251_ AHVSH 256_ LRDYP 261_ TYYTS 266_ LCVDF 271_MRNCV
1: Ensures normal bone formation, through the negative regulation of bone morphogenetic protein (BMP) signaling in osteoblast lineage cells by blocking cytoplasm-nucleus translocation of phosphorylated SMAD1/5/9 proteins