DnaJ homolog subfamily C member 24 (CSL-type zinc finger-containing protein 3) (Diphthamide biosynthesis protein 4)
1_MMAVE 6_ QMPKK 11_ DWYSI 16_ LGADP 21_ SANIS 26_ DLKQK 31_ YQKLI 36_ LMYHP 41_ DKQST 46_ DVPAG 51_ TVEEC 56_ VQKFI 61_ EIDQA 66_ WKILG 71_ NEETK 76_ REYDL 81_ QRCED 86_ DLRNV 91_ GPVDA 96_ QVYLE 101_ EMSWN 106_ EGDHS 111_ FYLSC 116_ RCGGK 121_ YSVSK 126_ DEAEE 131_ VSLIS 136_ CDTCS 141_LIIEL
1: Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta)