Gene name: C22orf39

Uniprot entry:

Q6P5X5

Protein names:

UPF0545 protein C22orf39

Protein sequence:

1_MCRCS 6_ LVLLS 11_ VDHEV 16_ PFSSF 21_ FIGWR 26_ TEGRA 31_ WRAGR 36_ PDMAD 41_ GSGWQ 46_ PPRPC 51_ EAYRA 56_ EWKLC 61_ RSARH 66_ FLHHY 71_ YVHGE 76_ RPACE 81_ QWQRD 86_ LASCR 91_ DWEER 96_ RNAEA 101_ QQSLC 106_ ESERA 111_ RVRAA 116_ RKHIL 121_ VWAPR 126_ QSPPP 131_ DWHLP 136_LPQEK

Protein annotations

Protein functions:

1: Negatively regulates long-term potentiation and modulates adult synaptic plasticity. Stabilizes the interaction of RTN4 isoform A/Nogo-A with its receptors, inhibiting clustering of postsynaptic AMPA receptors at synaptic sites. Upon neuronal stimulation, degraded at synapses, reducing RTN4 signaling and allowing AMPA receptor clustering at individual synapses