Forkhead box protein R1 (Forkhead box protein N5)
1_MGNEL 6_ FLAFT 11_ TSHLP 16_ LAEQK 21_ LARYK 26_ LRIVK 31_ PPKLP 36_ LEKKP 41_ NPDKD 46_ GPDYE 51_ PNLWM 56_ WVNPN 61_ IVYPP 66_ GKLEV 71_ SGRRK 76_ REDLT 81_ STLPS 86_ SQPPQ 91_ KEEDA 96_ SCSEA 101_ AGVES 106_ LSQSS 111_ SKRSP 116_ PRKRF 121_ AFSPS 126_ TWELT 131_ EEEEA 136_ EDQED 141_ SSSMA 146_ LPSPH 151_ KRAPL 156_ QSRRL 161_ RQASS 166_ QAGRL 171_ WSRPP 176_ LNYFH 181_ LIALA 186_ LRNSS 191_ PCGLN 196_ VQQIY 201_ SFTRK 206_ HFPFF 211_ RTAPE 216_ GWKNT 221_ VRHNL 226_ CFRDS 231_ FEKVP 236_ VSMQG 241_ GASTR 246_ PRSCL 251_ WKLTE 256_ EGHRR 261_ FAEEA 266_ RALAS 271_ TRLES 276_ IQQCM 281_ SQPDV 286_MPFLF
1: Transcription factor which acts as both an activator and a repressor (PubMed:34723967). Activates transcription of a number of genes including the heat shock chaperones HSPA1A and HSPA6 and the antioxidant NADPH-dependent reductase DHRS2 which are involved in protection against oxidative stress (PubMed:34723967). Required for normal brain development (By similarity)