Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1)
1_MSECG 6_ GRGGG 11_ SSSSE 16_ DAEDE 21_ GGGGG 26_ GPAGS 31_ DCLSS 36_ SPTLA 41_ TASSA 46_ GRLRR 51_ GLRGA 56_ FLMAR 61_ QRPEL 66_ LCGAV 71_ ALGCA 76_ LLLAL 81_ KFTCS 86_ RAKDV 91_ IIPAK 96_ PPVSF 101_ FSLRS 106_ PVLDL 111_ FQGQL 116_ DYAEY 121_ VRRDS 126_ EVVLL 131_ FFYAP 136_ WCGQS 141_ IAARA 146_ EIEQA 151_ ASRLS 156_ DQVLF 161_ VAINC 166_ WWNQG 171_ KCRKQ 176_ KHFFY 181_ FPVIY 186_ LYHRS 191_ FGPIE 196_ YKGPM 201_ SAVYI 206_ EKFVR 211_ RVMKP 216_ LLYIP 221_ SQSEL 226_ LDFLS 231_ NYEPG 236_ VLGYF 241_ EFSGS 246_ PQPPG 251_ YLTFF 256_ TSALH 261_ SLKKA 266_ LESTS 271_ SPRAL 276_ VSFTG 281_ EWHLE 286_ TKIYV 291_ LDYLG 296_ TVRFG 301_ VITNK 306_ HLAKL 311_ VSLVH 316_ SGSVY 321_ LHRHF 326_ NTSLV 331_ FPREV 336_ LNYTA 341_ ENICK 346_ WALEN 351_ QETLF 356_ RWLRP 361_ HGGKS 366_ LLLNN 371_ ELKKG 376_ PALFL 381_ FIPFN 386_ PLAES 391_ HPLID 396_ EITEV 401_ ALEYN 406_ NCHGD 411_ QVVER 416_ LLQHL 421_ RRVDA 426_ PVLES 431_ LALEV 436_ PAQLP 441_ DPPTI 446_ TASPC 451_ CNTVV 456_ LPQWH 461_ SFSRT 466_ HNVCE 471_ LCVNQ 476_ TSGGM 481_ KPSSV 486_ SVPQC 491_ SFFEM 496_ AAALD 501_ SFYLK 506_ EQTFY 511_ HVASD 516_ SIECS 521_ NFLTS 526_ YSPFS 531_ YYTAC 536_ CRTIS 541_ RGVSG 546_ FIDSE 551_ QGVFE 556_ APTVA 561_ FSSLE 566_ KKCEV 571_ DAPSS 576_ VPHIE 581_ ENRYL 586_ FPEVD 591_ MTSTN 596_ FTGLS 601_ CRTNK 606_ TLNIY 611_ LLDSN 616_ LFWLY 621_ AERLG 626_ APSST 631_ QVKEF 636_ AAIVD 641_ VKEES 646_ HYILD 651_ PKQAL 656_ MKLTL 661_ ESFIQ 666_ NFSVL 671_ YSPLK 676_ RHLIG 681_ SGSAQ 686_ FPSQH 691_ LITEV 696_ TTDTF 701_ WEVVL 706_ QKQDV 711_ LLLYY 716_ APWCG 721_ FCPSL 726_ NHIFI 731_ QLARN 736_ LPMDT 741_ FTVAR 746_ IDVSQ 751_ NDLPW 756_ EFMVD 761_ RLPTV 766_ LFFPC 771_ NRKDL 776_ SVKYP 781_ EDVPI 786_ TLPNL 791_ LRFIL 796_ HHSDP 801_ ASSPQ 806_ NVANS 811_ PTKEC 816_ LQSEA 821_ VLQRG 826_ HISHL 831_ EREIQ 836_ KLRAE 841_ ISSLQ 846_ RAQVQ 851_ VESQL 856_ SSARR 861_ DEHRL 866_ RQQQR 871_ ALEEQ 876_ HSLLH 881_ AHSEQ 886_ LQALY 891_ EQKTR 896_ ELQEL 901_ ARKLQ 906_ ELADA 911_ SENLL 916_ TENTW 921_ LKILV 926_ ATMER 931_ KLEGR 936_ DGAES 941_ LAAQR 946_ EVHPK 951_ QPEPS 956_ ATPQL 961_ PGSSP 966_ PPANV 971_ SATLV 976_SERNK
1: May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation