ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) (AAA nuclear coregulator cancer-associated protein) (ANCCA)
1_MVVLR 6_ SSLEL 11_ HNHSA 16_ ASATG 21_ SLDLS 26_ SDFLS 31_ LEHIG 36_ RRRLR 41_ SAGAA 46_ QKKPA 51_ ATTAK 56_ AGDGS 61_ SVKEV 66_ ETYHR 71_ TRALR 76_ SLRKD 81_ AQNSS 86_ DSSFE 91_ KNVEI 96_ TEQLA 101_ NGRHF 106_ TRQLA 111_ RQQAD 116_ KKKEE 121_ HREDK 126_ VIPVT 131_ RSLRA 136_ RNIVQ 141_ STEHL 146_ HEDNG 151_ DVEVR 156_ RSCRI 161_ RSRYS 166_ GVNQS 171_ MLFDK 176_ LITNT 181_ AEAVL 186_ QKMDD 191_ MKKMR 196_ RQRMR 201_ ELEDL 206_ GVFNE 211_ TEESN 216_ LNMYT 221_ RGKQK 226_ DIQRT 231_ DEETT 236_ DNQEG 241_ SVESS 246_ EEGED 251_ QEHED 256_ DGEDE 261_ DDEDD 266_ DDDDD 271_ DDDDD 276_ DDEDD 281_ EDEED 286_ GEEEN 291_ QKRYY 296_ LRQRK 301_ ATVYY 306_ QAPLE 311_ KPRHQ 316_ RKPNI 321_ FYSGP 326_ ASPAR 331_ PRYRL 336_ SSAGP 341_ RSPYC 346_ KRMNR 351_ RRHAI 356_ HSSDS 361_ TSSSS 366_ SEDEQ 371_ HFERR 376_ RKRSR 381_ NRAIN 386_ RCLPL 391_ NFRKD 396_ ELKGI 401_ YKDRM 406_ KIGAS 411_ LADVD 416_ PMQLD 421_ SSVRF 426_ DSVGG 431_ LSNHI 436_ AALKE 441_ MVVFP 446_ LLYPE 451_ VFEKF 456_ KIQPP 461_ RGCLF 466_ YGPPG 471_ TGKTL 476_ VARAL 481_ ANECS 486_ QGDKR 491_ VAFFM 496_ RKGAD 501_ CLSKW 506_ VGESE 511_ RQLRL 516_ LFDQA 521_ YQMRP 526_ SIIFF 531_ DEIDG 536_ LAPVR 541_ SSRQD 546_ QIHSS 551_ IVSTL 556_ LALMD 561_ GLDSR 566_ GEIVV 571_ IGATN 576_ RLDSI 581_ DPALR 586_ RPGRF 591_ DREFL 596_ FSLPD 601_ KEARK 606_ EILKI 611_ HTRDW 616_ NPKPL 621_ DTFLE 626_ ELAEN 631_ CVGYC 636_ GADIK 641_ SICAE 646_ AALCA 651_ LRRRY 656_ PQIYT 661_ TSEKL 666_ QLDLS 671_ SINIS 676_ AKDFE 681_ VAMQK 686_ MIPAS 691_ QRAVT 696_ SPGQA 701_ LSTVV 706_ KPLLQ 711_ NTVDK 716_ ILEAL 721_ QRVFP 726_ HAEFR 731_ TNKTL 736_ DSDIS 741_ CPLLE 746_ SDLAY 751_ SDDDV 756_ PSVYE 761_ NGLSQ 766_ KSSHK 771_ AKDNF 776_ NFLHL 781_ NRNAC 786_ YQPMS 791_ FRPRI 796_ LIVGE 801_ PGFGQ 806_ GSHLA 811_ PAVIH 816_ ALEKF 821_ TVYTL 826_ DIPVL 831_ FGVST 836_ TSPEE 841_ TCAQV 846_ IREAK 851_ RTAPS 856_ IVYVP 861_ HIHVW 866_ WEIVG 871_ PTLKA 876_ TFTTL 881_ LQNIP 886_ SFAPV 891_ LLLAT 896_ SDKPH 901_ SALPE 906_ EVQEL 911_ FIRDY 916_ GEIFN 921_ VQLPD 926_ KEERT 931_ KFFED 936_ LILKQ 941_ AAKPP 946_ ISKKK 951_ AVLQA 956_ LEVLP 961_ VAPPP 966_ EPRSL 971_ TAEEV 976_ KRLEE 981_ QEEDT 986_ FRELR 991_ IFLRN 996_ VTHRL 1001_ AIDKR 1006_ FRVFT 1011_ KPVDP 1016_ DEVPD 1021_ YVTVI 1026_ KQPMD 1031_ LSSVI 1036_ SKIDL 1041_ HKYLT 1046_ VKDYL 1051_ RDIDL 1056_ ICSNA 1061_ LEYNP 1066_ DRDPG 1071_ DRLIR 1076_ HRACA 1081_ LRDTA 1086_ YAIIK 1091_ EELDE 1096_ DFEQL 1101_ CEEIQ 1106_ ESRKK 1111_ RGCSS 1116_ SKYAP 1121_ SYYHV 1126_ MPKQN 1131_ STLVG 1136_ DKRSD 1141_ PEQNE 1146_ KLKTP 1151_ STPVA 1156_ CSTPA 1161_ QLKRK 1166_ IRKKS 1171_ NWYLG 1176_ TIKKR 1181_ RKISQ 1186_ AKDDS 1191_ QNAID 1196_ HKIES 1201_ DTEET 1206_ QDTSV 1211_ DHNET 1216_ GNTGE 1221_ SSVEE 1226_ NEKQQ 1231_ NASES 1236_ KLELR 1241_ NNSNT 1246_ CNIEN 1251_ ELEDS 1256_ RKTTA 1261_ CTELR 1266_ DKIAC 1271_ NGDAS 1276_ SSQII 1281_ HISDE 1286_ NEGKE 1291_ MCVLR 1296_ MTRAR 1301_ RSQVE 1306_ QQQLI 1311_ TVEKA 1316_ LAILS 1321_ QPTPS 1326_ LVVDH 1331_ ERLKN 1336_ LLKTV 1341_ VKKSQ 1346_ NYNIF 1351_ QLENL 1356_ YAVIS 1361_ QCIYR 1366_ HRKDH 1371_ DKTSL 1376_ IQKME 1381_QEVEN
1: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells