Probable G-protein coupled receptor 179 (Probable G-protein coupled receptor 158-like 1) (GPR158-like)
1_MGTRG 6_ AVMPP 11_ PMWGL 16_ LGCCF 21_ VCAWA 26_ LGGPR 31_ PIRSL 36_ PPLSS 41_ QVKPG 46_ SVPMQ 51_ VPLEG 56_ AEAAL 61_ AYLYS 66_ GDAQQ 71_ LSQVN 76_ CSERY 81_ EARGA 86_ GAMPG 91_ LPPSL 96_ QGAAG 101_ TLAQA 106_ ANFLN 111_ MLLQA 116_ NDIRE 121_ SSVEE 126_ DVEWY 131_ QALVR 136_ SVAEG 141_ DPRVY 146_ RALLT 151_ FNPPP 156_ GASHL 161_ QLALQ 166_ ATRTG 171_ EETIL 176_ QDLSG 181_ NWVQE 186_ ENPPG 191_ DLDTP 196_ ALKKR 201_ VLTND 206_ LGSLG 211_ SPKWP 216_ QADGY 221_ VGDTQ 226_ QVRLS 231_ PPFLE 236_ CQEGR 241_ LRPGW 246_ LITLS 251_ ATFYG 256_ LKPDL 261_ SPEVR 266_ GQVQM 271_ DVDLQ 276_ SVDIN 281_ QCASG 286_ PGWYS 291_ NTHLC 296_ DLNST 301_ QCVPL 306_ ESQGF 311_ VLGRY 316_ LCRCR 321_ PGFYG 326_ ASPSG 331_ GLEES 336_ DFQTT 341_ GQFGF 346_ PEGRS 351_ GRLLQ 356_ CLPCP 361_ EGCTS 366_ CMDAT 371_ PCLVE 376_ EAAVL 381_ RAAVL 386_ ACQAC 391_ CMLAI 396_ FLSML 401_ VSYRC 406_ RRNKR 411_ IWASG 416_ VVLLE 421_ TVLFG 426_ FLLLY 431_ FPVFI 436_ LYFKP 441_ SVFRC 446_ IALRW 451_ VRLLG 456_ FAIVY 461_ GTIIL 466_ KLYRV 471_ LQLFL 476_ SRTAQ 481_ RSALL 486_ SSGRL 491_ LRRLG 496_ LLLLP 501_ VLGFL 506_ AVWTV 511_ GALER 516_ GIQHA 521_ PLVIR 526_ GHTPS 531_ GRHFY 536_ LCHHD 541_ RWDYI 546_ MVVAE 551_ LLLLC 556_ WGSFL 561_ CYATR 566_ AVLSA 571_ FHEPR 576_ YMGIA 581_ LHNEL 586_ LLSAA 591_ FHTAR 596_ FVLVP 601_ SLHPD 606_ WTLLL 611_ FFFHT 616_ HSTVT 621_ TTLAL 626_ IFIPK 631_ FWKLG 636_ APPRE 641_ EMVDE 646_ VCEDE 651_ LDLQH 656_ SGSYL 661_ GSSIA 666_ SAWSE 671_ HSLDP 676_ GDIRD 681_ ELKKL 686_ YAQLE 691_ VHKTK 696_ EMAAN 701_ NPHLP 706_ KKRGS 711_ SCQGL 716_ GRSFM 721_ RYLAE 726_ FPEAL 731_ ARQHS 736_ RDSGS 741_ PGHGS 746_ LPGSS 751_ RRRLL 756_ SSSLQ 761_ EPEGT 766_ PALHK 771_ SRSTY 776_ DQRRE 781_ QDPPL 786_ LDSLL 791_ RRKLA 796_ KKASR 801_ TESRE 806_ SVEGP 811_ PALGF 816_ RSASA 821_ HNLTV 826_ GERLP 831_ RARPA 836_ SLQKS 841_ LSVAS 846_ SREKA 851_ LLMAS 856_ QAYLE 861_ ETYRQ 866_ AKERE 871_ ERKKA 876_ KAAMA 881_ SLVRR 886_ PSARR 891_ LERPR 896_ GAPLS 901_ APPSP 906_ AKSSS 911_ VDSSH 916_ TSGRL 921_ HEEAR 926_ RRLPH 931_ PPIRH 936_ QVSTP 941_ ILALS 946_ GGLGE 951_ PRMLS 956_ PTSTL 961_ APALL 966_ PALAP 971_ TPAPA 976_ LAPVP 981_ VSPQS 986_ PNLLT 991_ YICPW 996_ ENAEL 1001_ PAKQE 1006_ NVPQE 1011_ GPSGP 1016_ ERGHH 1021_ SPAPA 1026_ RARLW 1031_ RALSV 1036_ AVEKS 1041_ RAGEN 1046_ EMDAE 1051_ DAHHQ 1056_ REAND 1061_ VDEDR 1066_ PKIFP 1071_ KSHSL 1076_ KAPVQ 1081_ QGSMR 1086_ SLGLA 1091_ IKALT 1096_ RSRST 1101_ YREKE 1106_ SVEES 1111_ PEGQN 1116_ SGTAG 1121_ ESMGA 1126_ PSRSP 1131_ RLGRP 1136_ KAVSK 1141_ QAALI 1146_ PSDDK 1151_ ESLQN 1156_ QQNAH 1161_ TSRML 1166_ QVCQR 1171_ EGSRE 1176_ QEDRG 1181_ RRMTQ 1186_ GLGER 1191_ KAERA 1196_ GKTGL 1201_ AMLRQ 1206_ VSRDK 1211_ NIKQS 1216_ KETPV 1221_ GWQEL 1226_ PKAGL 1231_ QSLGS 1236_ ADHRV 1241_ AEVCP 1246_ WEVTE 1251_ SETRQ 1256_ PDSGN 1261_ KAEIC 1266_ PWETS 1271_ EGAPE 1276_ SRALR 1281_ QDPGD 1286_ SQKKR 1291_ GEARG 1296_ KSEPI 1301_ DVVPM 1306_ MRKKP 1311_ ERLVR 1316_ EQEAV 1321_ CPWES 1326_ ADRGG 1331_ LSPGS 1336_ APQDP 1341_ GRIRD 1346_ KSEAG 1351_ DSVEA 1356_ RKVEK 1361_ PGWEA 1366_ AGPEA 1371_ HTPDI 1376_ TKAEP 1381_ CPWEA 1386_ SEGGE 1391_ DGKPA 1396_ QEAVK 1401_ DLPQE 1406_ KQKTR 1411_ KATFW 1416_ KEQKP 1421_ GGDLE 1426_ SLCPW 1431_ ESTDF 1436_ RGPSA 1441_ VSIQA 1446_ PGSSE 1451_ CSGSL 1456_ GSGIA 1461_ EVCLW 1466_ EAGDA 1471_ PAIQK 1476_ AEICP 1481_ WELDD 1486_ NVMGQ 1491_ EMLSL 1496_ GTGRE 1501_ SLQEK 1506_ EKASR 1511_ KGSFG 1516_ EMGEQ 1521_ TVKAV 1526_ QKLSQ 1531_ QQESV 1536_ CPRES 1541_ TVPGH 1546_ SSPCL 1551_ DNSSS 1556_ KAGSQ 1561_ FLCNG 1566_ GSRAT 1571_ QVCPQ 1576_ EDLRP 1581_ EAQEA 1586_ TPAKT 1591_ EICPW 1596_ EVNER 1601_ TREEW 1606_ TSAQV 1611_ PRGGE 1616_ SQKDK 1621_ EKMPG 1626_ KSEIE 1631_ DVTAW 1636_ EKPEG 1641_ QIQKQ 1646_ EAVGP 1651_ WESVD 1656_ PGSFS 1661_ PQPRP 1666_ QDTER 1671_ PQTLL 1676_ QMSGS 1681_ VGSKA 1686_ ADICP 1691_ LDVEE 1696_ NLTAG 1701_ KAEIC 1706_ PWEVG 1711_ AGAGE 1716_ ERALG 1721_ AEAIR 1726_ KSPND 1731_ TGKVS 1736_ ADLGP 1741_ RERAV 1746_ TAPEK 1751_ PQKPT 1756_ PEWEV 1761_ ACPWG 1766_ SVGPG 1771_ ACSQH 1776_ PGTLD 1781_ ADGPK 1786_ AGFQE 1791_ LDHMG 1796_ CRPGE 1801_ VCPWE 1806_ AQEAA 1811_ TSEKA 1816_ KICPW 1821_ EVSEG 1826_ TTGKG 1831_ LDQKA 1836_ GSESA 1841_ EQREK 1846_ ALEKG 1851_ RLTSL 1856_ GEDVS 1861_ KGMAK 1866_ LCQQQ 1871_ ETICI 1876_ WENKD 1881_ LRESP 1886_ AQAPK 1891_ ISDLP 1896_ SSMSS 1901_ EVAEG 1906_ HSLEA 1911_ TEKGD 1916_ LRQDP 1921_ KTGSF 1926_ PEHIT 1931_ QEKAP 1936_ AADTE 1941_ EFTTE 1946_ DGEKT 1951_ SHELQ 1956_ SVCPW 1961_ ETTAP 1966_ ADSVS 1971_ HLDRQ 1976_ RPDQP 1981_ KASSQ 1986_ RLVST 1991_ GGRAA 1996_ DVCPW 2001_ DVPDA 2006_ GVYKS 2011_ DSSAK 2016_ AETCP 2021_ WEVTE 2026_ RIPVK 2031_ GVSRQ 2036_ DGKGD 2041_ SQEEK 2046_ GRAPE 2051_ KSEPK 2056_ GVPVQ 2061_ KKPEM 2066_ ADFRQ 2071_ QEAVC 2076_ PWESQ 2081_ DGKGL 2086_ SPQPA 2091_ PDASD 2096_ RSRGS 2101_ SEAAG 2106_ SVETR 2111_ VAEVC 2116_ LWEVV 2121_ EAPSA 2126_ KKAEI 2131_ CPWEA 2136_ GGGAA 2141_ EEGEQ 2146_ ERESQ 2151_ GQGEM 2156_ FLQKA 2161_ GPGGT 2166_ EEHFS 2171_ KAAAK 2176_ PREQE 2181_ AVCPG 2186_ EGTGS 2191_ GGLLP 2196_ QSGAL 2201_ DPELK 2206_ VSPKE 2211_ AGSMG 2216_ SRMAE 2221_ LCQWE 2226_ ITDPE 2231_ GNKIK 2236_ GTMAD 2241_ ICPGE 2246_ ETGVP 2251_ SEESG 2256_ LLALT 2261_ ATRRE 2266_ FFPTA 2271_ PEKPL 2276_ CLLVH 2281_ GPLDH 2286_ FFPES 2291_ KIPCP 2296_ KVSRP 2301_ ASTFT 2306_ LEGVR 2311_ ELQGP 2316_ SGLEP 2321_ RTSLA 2326_ PEPSL 2331_ QEAES 2336_ QSSSL 2341_ TEDSG 2346_ QVAFE 2351_ AQYEE 2356_ FTPPT 2361_VYPWD
1: Orphan receptor involved in vision (PubMed:22325362, PubMed:24084093). Required for signal transduction through retinal depolarizing bipolar cells (PubMed:22325362). Acts as an atypical G-protein coupled receptor that recruits and regulates the R7 group RGS-GNB5 complexes instead of activating G proteins: promotes the GTPase activator activity of R7 RGS proteins, increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (By similarity). Associates with components of metabotropic signaling cascade in retina ON-bipolar neurons, such as TRPM1 and GRM6: may control the ability of the GRM6 cascade to gate TRPM1 (By similarity)