Type-1 angiotensin II receptor-associated protein (AT1 receptor-associated protein)
1_MELPA 6_ VNLKV 11_ ILLGH 16_ WLLTT 21_ WGCIV 26_ FSGSY 31_ AWANF 36_ TILAL 41_ GVWAV 46_ AQRDS 51_ IDAIS 56_ MFLGG 61_ LLATI 66_ FLDIV 71_ HISIF 76_ YPRVS 81_ LTDTG 86_ RFGVG 91_ MAILS 96_ LLLKP 101_ LSCCF 106_ VYHMY 111_ RERGG 116_ ELLVH 121_ TGFLG 126_ SSQDR 131_ SAYQT 136_ IDSAE 141_ APADP 146_ FAVPE 151_GRSQD
1: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Also induces a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity