Gene name: PAQR6

Uniprot entry:

Q6TCH4

Protein names:

Membrane progestin receptor delta (mPR delta) (Membrane progesterone P4 receptor delta) (Membrane progesterone receptor delta) (Progesterone and adipoQ receptor family member 6) (Progestin and adipoQ receptor family member 6)

Protein sequence:

1_MLSLK 6_ LPQLL 11_ QVHQV 16_ PRVFW 21_ EDGIM 26_ SGYRR 31_ PTSSA 36_ LDCVL 41_ SSFQM 46_ TNETV 51_ NIWTH 56_ FLPTW 61_ YFLWR 66_ LLALA 71_ GGPGF 76_ RAEPY 81_ HWPLL 86_ VFLLP 91_ ACLYP 96_ FASCC 101_ AHTFS 106_ SMSPR 111_ MRHIC 116_ YFLDY 121_ GALSL 126_ YSLGC 131_ AFPYA 136_ AYSMP 141_ ASWLH 146_ GHLHQ 151_ FFVPA 156_ AALNS 161_ FLCTG 166_ LSCYS 171_ RFLEL 176_ ESPGL 181_ SKVLR 186_ TGAFA 191_ YPFLF 196_ DNLPL 201_ FYRLG 206_ LCWGR 211_ GHGCG 216_ QEALS 221_ TSHGY 226_ HLFCA 231_ LLTGF 236_ LFASH 241_ LPERL 246_ APGRF 251_ DYIGH 256_ SHQLF 261_ HICAV 266_ LGTHF 271_ QLEAV 276_ LADMG 281_ SRRAW 286_ LATQE 291_ PALGL 296_ AGTVA 301_ TLVLA 306_ AAGNL 311_ LIIAA 316_ FTATL 321_ LRAPS 326_ TCPLL 331_ QGGPL 336_EGGTQ

Protein annotations

Protein functions:

1: Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23161870, PubMed:23763432). Seems to act through a G(s) mediated pathway (PubMed:23161870). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870, PubMed:23763432)