Protein-arginine deiminase type-6 (EC 3.5.3.15) (Peptidyl arginine deiminase-like protein) (Peptidylarginine deiminase VI) (hPADVI) (Protein-arginine deiminase type VI)
1_MVSVE 6_ GRAMS 11_ FQSII 16_ HLSLD 21_ SPVHA 26_ VCVLG 31_ TEICL 36_ DLSGC 41_ APQKC 46_ QCFTI 51_ HGSGR 56_ VLIDV 61_ ANTVI 66_ SEKED 71_ ATIWW 76_ PLSDP 81_ TYATV 86_ KMTSP 91_ SPSVD 96_ ADKVS 101_ VTYYG 106_ PNEDA 111_ PVGTA 116_ VLYLT 121_ GIEVS 126_ LEVDI 131_ YRNGQ 136_ VEMSS 141_ DKQAK 146_ KKWIW 151_ GPSGW 156_ GAILL 161_ VNCNP 166_ ADVGQ 171_ QLEDK 176_ KTKKV 181_ IFSEE 186_ ITNLS 191_ QMTLN 196_ VQGPS 201_ CILKK 206_ YRLVL 211_ HTSKE 216_ ESKKA 221_ RVYWP 226_ QKDNS 231_ STFEL 236_ VLGPD 241_ QHAYT 246_ LALLG 251_ NHLKE 256_ TFYVE 261_ AIAFP 266_ SAEFS 271_ GLISY 276_ SVSLV 281_ EESQD 286_ PSIPE 291_ TVLYK 296_ DTVVF 301_ RVAPC 306_ VFIPC 311_ TQVPL 316_ EVYLC 321_ RELQL 326_ QGFVD 331_ TVTKL 336_ SEKSN 341_ SQVAS 346_ VYEDP 351_ NRLGR 356_ WLQDE 361_ MAFCY 366_ TQAPH 371_ KTTSL 376_ ILDTP 381_ QAADL 386_ DEFPM 391_ KYSLS 396_ PGIGY 401_ MIQDT 406_ EDHKV 411_ ASMDS 416_ IGNLM 421_ VSPPV 426_ KVQGK 431_ EYPLG 436_ RVLIG 441_ SSFYP 446_ SAEGR 451_ AMSKT 456_ LRDFL 461_ YAQQV 466_ QAPVE 471_ LYSDW 476_ LMTGH 481_ VDEFM 486_ CFIPT 491_ DDKNE 496_ GKKGF 501_ LLLLA 506_ SPSAC 511_ YKLFR 516_ EKQKE 521_ GYGDA 526_ LLFDE 531_ LRADQ 536_ LLSNG 541_ REAKT 546_ IDQLL 551_ ADESL 556_ KKQNE 561_ YVEKC 566_ IHLNR 571_ DILKT 576_ ELGLV 581_ EQDII 586_ EIPQL 591_ FCLEK 596_ LTNIP 601_ SDQQP 606_ KRSFA 611_ RPYFP 616_ DLLRM 621_ IVMGK 626_ NLGIP 631_ KPFGP 636_ QIKGT 641_ CCLEE 646_ KICCL 651_ LEPLG 656_ FKCTF 661_ INDFD 666_ CYLTE 671_ VGDIC 676_ ACANI 681_ RRVPF 686_AFKWW
1: Structural constituent of cytoplasmic lattices, which plays a key role in early embryonic development (PubMed:37922900). Cytoplasmic lattices consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos (PubMed:37922900). They are required to store maternal proteins critical for embryonic development, such as ribosomal proteins and proteins that control epigenetic reprogramming of the preimplantation embryo, and prevent their degradation or activation (PubMed:37922900). In contrast to other members of the family, does not show protein-arginine deiminase activity due to its inability to bind Ca(2+) (PubMed:38656308, PubMed:39286527)