Zinc finger protein 322 (Zinc finger protein 322A) (Zinc finger protein 388) (Zinc finger protein 489)
1_MYTSE 6_ EKCNQ 11_ RTQKR 16_ KIYNV 21_ CPRKG 26_ KKIFI 31_ HMHEI 36_ IQIDG 41_ HIYQC 46_ LECKQ 51_ NFCEN 56_ LALIM 61_ CERTH 66_ TGEKP 71_ YKCDM 76_ CEKTF 81_ VQSSD 86_ LTSHQ 91_ RIHNY 96_ EKPYK 101_ CSKCE 106_ KSFWH 111_ HLALS 116_ GHQRT 121_ HAGKK 126_ FYTCD 131_ ICGKN 136_ FGQSS 141_ DLLVH 146_ QRSHT 151_ GEKPY 156_ LCSEC 161_ DKCFS 166_ RSTNL 171_ IRHRR 176_ THTGE 181_ KPFKC 186_ LECEK 191_ AFSGK 196_ SDLIS 201_ HQRTH 206_ TGERP 211_ YKCNK 216_ CEKSY 221_ RHRSA 226_ FIVHK 231_ RVHTG 236_ EKPYK 241_ CGACE 246_ KCFGQ 251_ KSDLI 256_ VHQRV 261_ HTGEK 266_ PYKCL 271_ ECMRS 276_ FTRSA 281_ NLIRH 286_ QATHT 291_ HTFKC 296_ LEYEK 301_ SFNCS 306_ SDLIV 311_ HQRIH 316_ MEEKP 321_ HQWSA 326_ CESGF 331_ LLGMD 336_ FVAQQ 341_ KMRTQ 346_ TEELH 351_ YKYTV 356_ CDKSF 361_ HQSSA 366_ LLQHQ 371_ TVHIG 376_ EKPFV 381_ CNVSE 386_ KGLEL 391_ SPPHA 396_SEASQ
1: Transcriptional activator (PubMed:15555580). Important for maintenance of pluripotency in embryonic stem cells (By similarity). Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes (By similarity). Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly (By similarity). Promotes inhibition of MAPK signaling during embryonic stem cell differentiation (By similarity)