CREB-regulated transcription coactivator 3 (Transducer of regulated cAMP response element-binding protein 3) (TORC-3) (Transducer of CREB protein 3)
1_MAASP 6_ GSGSA 11_ NPRKF 16_ SEKIA 21_ LHTQR 26_ QAEET 31_ RAFEQ 36_ LMTDL 41_ TLSRV 46_ QFQKL 51_ QQLRL 56_ TQYHG 61_ GSLPN 66_ VSQLR 71_ SSASE 76_ FQPSF 81_ HQADN 86_ VRGTR 91_ HHGLV 96_ ERPSR 101_ NRFHP 106_ LHRRS 111_ GDKPG 116_ RQFDG 121_ SAFGA 126_ NYSSQ 131_ PLDES 136_ WPRQQ 141_ PPWKD 146_ EKHPG 151_ FRLTS 156_ ALNRT 161_ NSDSA 166_ LHTSA 171_ LSTKP 176_ QDPYG 181_ GGGQS 186_ AWPAP 191_ YMGFC 196_ DGENN 201_ GHGEV 206_ ASFPG 211_ PLKEE 216_ NLLNV 221_ PKPLP 226_ KQLWE 231_ TKEIQ 236_ SLSGR 241_ PRSCD 246_ VGGGN 251_ AFPHN 256_ GQNLG 261_ LSPFL 266_ GTLNT 271_ GGSLP 276_ DLTNL 281_ HYSTP 286_ LPASL 291_ DTTDH 296_ HFGSM 301_ SVGNS 306_ VNNIP 311_ AAMTH 316_ LGIRS 321_ SSGLQ 326_ SSRSN 331_ PSIQA 336_ TLNKT 341_ VLSSS 346_ LNNHP 351_ QTSVP 356_ NASAL 361_ HPSLR 366_ LFSLS 371_ NPSLS 376_ TTNLS 381_ GPSRR 386_ RQPPV 391_ SPLTL 396_ SPGPE 401_ AHQGF 406_ SRQLS 411_ STSPL 416_ APYPT 421_ SQMVS 426_ SDRSQ 431_ LSFLP 436_ TEAQA 441_ QVSPP 446_ PPYPA 451_ PQELT 456_ QPLLQ 461_ QPRAP 466_ EAPAQ 471_ QPQAA 476_ SSLPQ 481_ SDFQL 486_ LPAQG 491_ SSLTN 496_ FFPDV 501_ GFDQQ 506_ SMRPG 511_ PAFPQ 516_ QVPLV 521_ QQGSR 526_ ELQDS 531_ FHLRP 536_ SPYSN 541_ CGSLP 546_ NTILP 551_ EDSST 556_ SLFKD 561_ LNSAL 566_ AGLPE 571_ VSLNV 576_ DTPFP 581_ LEEEL 586_ QIEPL 591_ SLDGL 596_ NMLSD 601_ SSMGL 606_ LDPSV 611_EETFR
1: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)