Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan)
1_MQSGP 6_ RPPLP 11_ APGLA 16_ LALTL 21_ TMLAR 26_ LASAA 31_ SFFGE 36_ NHLEV 41_ PVATA 46_ LTDID 51_ LQLQF 56_ STSQP 61_ EALLL 66_ LAAGP 71_ ADHLL 76_ LQLYS 81_ GRLQV 86_ RLVLG 91_ QEELR 96_ LQTPA 101_ ETLLS 106_ DSIPH 111_ TVVLT 116_ VVEGW 121_ ATLSV 126_ DGFLN 131_ ASSAV 136_ PGAPL 141_ EVPYG 146_ LFVGG 151_ TGTLG 156_ LPYLR 161_ GTSRP 166_ LRGCL 171_ HAATL 176_ NGRSL 181_ LRPLT 186_ PDVHE 191_ GCAEE 196_ FSASD 201_ DVALG 206_ FSGPH 211_ SLAAF 216_ PAWGT 221_ QDEGT 226_ LEFTL 231_ TTQSR 236_ QAPLA 241_ FQAGG 246_ RRGDF 251_ IYVDI 256_ FEGHL 261_ RAVVE 266_ KGQGT 271_ VLLHN 276_ SVPVA 281_ DGQPH 286_ EVSVH 291_ INAHR 296_ LEISV 301_ DQYPT 306_ HTSNR 311_ GVLSY 316_ LEPRG 321_ SLLLG 326_ GLDAE 331_ ASRHL 336_ QEHRL 341_ GLTPE 346_ ATNAS 351_ LLGCM 356_ EDLSV 361_ NGQRR 366_ GLREA 371_ LLTRN 376_ MAAGC 381_ RLEEE 386_ EYEDD 391_ AYGHY 396_ EAFST 401_ LAPEA 406_ WPAME 411_ LPEPC 416_ VPEPG 421_ LPPVF 426_ ANFTQ 431_ LLTIS 436_ PLVVA 441_ EGGTA 446_ WLEWR 451_ HVQPT 456_ LDLME 461_ AELRK 466_ SQVLF 471_ SVTRG 476_ ARHGE 481_ LELDI 486_ PGAQA 491_ RKMFT 496_ LLDVV 501_ NRKAR 506_ FIHDG 511_ SEDTS 516_ DQLVL 521_ EVSVT 526_ ARVPM 531_ PSCLR 536_ RGQTY 541_ LLPIQ 546_ VNPVN 551_ DPPHI 556_ IFPHG 561_ SLMVI 566_ LEHTQ 571_ KPLGP 576_ EVFQA 581_ YDPDS 586_ ACEGL 591_ TFQVL 596_ GTSSG 601_ LPVER 606_ RDQPG 611_ EPATE 616_ FSCRE 621_ LEAGS 626_ LVYVH 631_ RGGPA 636_ QDLTF 641_ RVSDG 646_ LQASP 651_ PATLK 656_ VVAIR 661_ PAIQI 666_ HRSTG 671_ LRLAQ 676_ GSAMP 681_ ILPAN 686_ LSVET 691_ NAVGQ 696_ DVSVL 701_ FRVTG 706_ ALQFG 711_ ELQKQ 716_ GAGGV 721_ EGAEW 726_ WATQA 731_ FHQRD 736_ VEQGR 741_ VRYLS 746_ TDPQH 751_ HAYDT 756_ VENLA 761_ LEVQV 766_ GQEIL 771_ SNLSF 776_ PVTIQ 781_ RATVW 786_ MLRLE 791_ PLHTQ 796_ NTQQE 801_ TLTTA 806_ HLEAT 811_ LEEAG 816_ PSPPT 821_ FHYEV 826_ VQAPR 831_ KGNLQ 836_ LQGTR 841_ LSDGQ 846_ GFTQD 851_ DIQAG 856_ RVTYG 861_ ATARA 866_ SEAVE 871_ DTFRF 876_ RVTAP 881_ PYFSP 886_ LYTFP 891_ IHIGG 896_ DPDAP 901_ VLTNV 906_ LLVVP 911_ EGGEG 916_ VLSAD 921_ HLFVK 926_ SLNSA 931_ SYLYE 936_ VMERP 941_ RHGRL 946_ AWRGT 951_ QDKTT 956_ MVTSF 961_ TNEDL 966_ LRGRL 971_ VYQHD 976_ DSETT 981_ EDDIP 986_ FVATR 991_ QGESS 996_ GDMAW 1001_ EEVRG 1006_ VFRVA 1011_ IQPVN 1016_ DHAPV 1021_ QTISR 1026_ IFHVA 1031_ RGGRR 1036_ LLTTD 1041_ DVAFS 1046_ DADSG 1051_ FADAQ 1056_ LVLTR 1061_ KDLLF 1066_ GSIVA 1071_ VDEPT 1076_ RPIYR 1081_ FTQED 1086_ LRKRR 1091_ VLFVH 1096_ SGADR 1101_ GWIQL 1106_ QVSDG 1111_ QHQAT 1116_ ALLEV 1121_ QASEP 1126_ YLRVA 1131_ NGSSL 1136_ VVPQG 1141_ GQGTI 1146_ DTAVL 1151_ HLDTN 1156_ LDIRS 1161_ GDEVH 1166_ YHVTA 1171_ GPRWG 1176_ QLVRA 1181_ GQPAT 1186_ AFSQQ 1191_ DLLDG 1196_ AVLYS 1201_ HNGSL 1206_ SPRDT 1211_ MAFSV 1216_ EAGPV 1221_ HTDAT 1226_ LQVTI 1231_ ALEGP 1236_ LAPLK 1241_ LVRHK 1246_ KIYVF 1251_ QGEAA 1256_ EIRRD 1261_ QLEAA 1266_ QEAVP 1271_ PADIV 1276_ FSVKS 1281_ PPSAG 1286_ YLVMV 1291_ SRGAL 1296_ ADEPP 1301_ SLDPV 1306_ QSFSQ 1311_ EAVDT 1316_ GRVLY 1321_ LHSRP 1326_ EAWSD 1331_ AFSLD 1336_ VASGL 1341_ GAPLE 1346_ GVLVE 1351_ LEVLP 1356_ AAIPL 1361_ EAQNF 1366_ SVPEG 1371_ GSLTL 1376_ APPLL 1381_ RVSGP 1386_ YFPTL 1391_ LGLSL 1396_ QVLEP 1401_ PQHGA 1406_ LQKED 1411_ GPQAR 1416_ TLSAF 1421_ SWRMV 1426_ EEQLI 1431_ RYVHD 1436_ GSETL 1441_ TDSFV 1446_ LMANA 1451_ SEMDR 1456_ QSHPV 1461_ AFTVT 1466_ VLPVN 1471_ DQPPI 1476_ LTTNT 1481_ GLQMW 1486_ EGATA 1491_ PIPAE 1496_ ALRST 1501_ DGDSG 1506_ SEDLV 1511_ YTIEQ 1516_ PSNGR 1521_ VVLRG 1526_ APGTE 1531_ VRSFT 1536_ QAQLD 1541_ GGLVL 1546_ FSHRG 1551_ TLDGG 1556_ FRFRL 1561_ SDGEH 1566_ TSPGH 1571_ FFRVT 1576_ AQKQV 1581_ LLSLK 1586_ GSQTL 1591_ TVCPG 1596_ SVQPL 1601_ SSQTL 1606_ RASSS 1611_ AGTDP 1616_ QLLLY 1621_ RVVRG 1626_ PQLGR 1631_ LFHAQ 1636_ QDSTG 1641_ EALVN 1646_ FTQAE 1651_ VYAGN 1656_ ILYEH 1661_ EMPPE 1666_ PFWEA 1671_ HDTLE 1676_ LQLSS 1681_ PPARD 1686_ VAATL 1691_ AVAVS 1696_ FEAAC 1701_ PQRPS 1706_ HLWKN 1711_ KGLWV 1716_ PEGQR 1721_ ARITV 1726_ AALDA 1731_ SNLLA 1736_ SVPSP 1741_ QRSEH 1746_ DVLFQ 1751_ VTQFP 1756_ SRGQL 1761_ LVSEE 1766_ PLHAG 1771_ QPHFL 1776_ QSQLA 1781_ AGQLV 1786_ YAHGG 1791_ GGTQQ 1796_ DGFHF 1801_ RAHLQ 1806_ GPAGA 1811_ SVAGP 1816_ QTSEA 1821_ FAITV 1826_ RDVNE 1831_ RPPQP 1836_ QASVP 1841_ LRLTR 1846_ GSRAP 1851_ ISRAQ 1856_ LSVVD 1861_ PDSAP 1866_ GEIEY 1871_ EVQRA 1876_ PHNGF 1881_ LSLVG 1886_ GGLGP 1891_ VTRFT 1896_ QADVD 1901_ SGRLA 1906_ FVANG 1911_ SSVAG 1916_ IFQLS 1921_ MSDGA 1926_ SPPLP 1931_ MSLAV 1936_ DILPS 1941_ AIEVQ 1946_ LRAPL 1951_ EVPQA 1956_ LGRSS 1961_ LSQQQ 1966_ LRVVS 1971_ DREEP 1976_ EAAYR 1981_ LIQGP 1986_ QYGHL 1991_ LVGGR 1996_ PTSAF 2001_ SQFQI 2006_ DQGEV 2011_ VFAFT 2016_ NFSSS 2021_ HDHFR 2026_ VLALA 2031_ RGVNA 2036_ SAVVN 2041_ VTVRA 2046_ LLHVW 2051_ AGGPW 2056_ PQGAT 2061_ LRLDP 2066_ TVLDA 2071_ GELAN 2076_ RTGSV 2081_ PRFRL 2086_ LEGPR 2091_ HGRVV 2096_ RVPRA 2101_ RTEPG 2106_ GSQLV 2111_ EQFTQ 2116_ QDLED 2121_ GRLGL 2126_ EVGRP 2131_ EGRAP 2136_ GPAGD 2141_ SLTLE 2146_ LWAQG 2151_ VPPAV 2156_ ASLDF 2161_ ATEPY 2166_ NAARP 2171_ YSVAL 2176_ LSVPE 2181_ AARTE 2186_ AGKPE 2191_ SSTPT 2196_ GEPGP 2201_ MASSP 2206_ EPAVA 2211_ KGGFL 2216_ SFLEA 2221_ NMFSV 2226_ IIPMC 2231_ LVLLL 2236_ LALIL 2241_ PLLFY 2246_ LRKRN 2251_ KTGKH 2256_ DVQVL 2261_ TAKPR 2266_ NGLAG 2271_ DTETF 2276_ RKVEP 2281_ GQAIP 2286_ LTAVP 2291_ GQGPP 2296_ PGGQP 2301_ DPELL 2306_ QFCRT 2311_ PNPAL 2316_KNGQY
1: Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Also functions as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades