Transmembrane protein 108 (Retrolinkin)
1_MKRSL 6_ QALYC 11_ QLLSF 16_ LLILA 21_ LTEAL 26_ AFAIQ 31_ EPSPR 36_ ESLQV 41_ LPSGT 46_ PPGTM 51_ VTAPH 56_ SSTRH 61_ TSVVM 66_ LTPNP 71_ DGPPS 76_ QAAAP 81_ MATPT 86_ PRAEG 91_ HPPTH 96_ TISTI 101_ AATVT 106_ APHSE 111_ SSLST 116_ GPAPA 121_ AMATT 126_ SSKPE 131_ GRPRG 136_ QAAPT 141_ ILLTK 146_ PPGAT 151_ SRPTT 156_ APPRT 161_ TTRRP 166_ PRPPG 171_ SSRKG 176_ AGNSS 181_ RPVPP 186_ APGGH 191_ SRSKE 196_ GQRGR 201_ NPSST 206_ PLGQK 211_ RPLGK 216_ IFQIY 221_ KGNFT 226_ GSVEP 231_ EPSTL 236_ TPRTP 241_ LWGYS 246_ SSPQP 251_ QTVAA 256_ TTVPS 261_ NTSWA 266_ PTTTS 271_ LGPAK 276_ DKPGL 281_ RRAAQ 286_ GGGST 291_ FTSQG 296_ GTPDA 301_ TAASG 306_ APVSP 311_ QAAPV 316_ PSQRP 321_ HHGDP 326_ QDGPS 331_ HSDSW 336_ LTVTP 341_ GTSRP 346_ LSTSS 351_ GVFTA 356_ ATGPT 361_ PAAFD 366_ TSVSA 371_ PSQGI 376_ PQGAS 381_ TTPQA 386_ PTHPS 391_ RVSES 396_ TISGA 401_ KEETV 406_ ATLTM 411_ TDRVP 416_ SPLST 421_ VVSTA 426_ TGNFL 431_ NRLVP 436_ AGTWK 441_ PGTAG 446_ NISHV 451_ AEGDK 456_ PQHRA 461_ TICLS 466_ KMDIA 471_ WVILA 476_ ISVPI 481_ SSCSV 486_ LLTVC 491_ CMKRK 496_ KKTAN 501_ PENNL 506_ SYWNN 511_ TITMD 516_ YFNRH 521_ AVELP 526_ REIQS 531_ LETSE 536_ DQLSE 541_ PRSPA 546_ NGDYR 551_ DTGMV 556_ LVNPF 561_ CQETL 566_FVGND
1: Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 and recruits the WAVE1 complex to facilitate actin-dependent BDNF:NTRK2 early endocytic trafficking and mediate signaling from early endosomes