Sclerostin domain-containing protein 1 (Ectodermal BMP inhibitor) (Ectodin) (Uterine sensitization-associated gene 1 protein) (USAG-1)
1_MLPPA 6_ IHFYL 11_ LPLAC 16_ ILMKS 21_ CLAFK 26_ NDATE 31_ ILYSH 36_ VVKPV 41_ PAHPS 46_ SNSTL 51_ NQARN 56_ GGRHF 61_ SNTGL 66_ DRNTR 71_ VQVGC 76_ RELRS 81_ TKYIS 86_ DGQCT 91_ SISPL 96_ KELVC 101_ AGECL 106_ PLPVL 111_ PNWIG 116_ GGYGT 121_ KYWSR 126_ RSSQE 131_ WRCVN 136_ DKTRT 141_ QRIQL 146_ QCQDG 151_ STRTY 156_ KITVV 161_ TACKC 166_ KRYTR 171_ QHNES 176_ SHNFE 181_ SMSPA 186_ KPVQH 191_ HRERK 196_ RASKS 201_SKHSM
1: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner