Synaptotagmin-10 (Synaptotagmin X) (SytX)
1_MSFHK 6_ EDGVN 11_ SLCQK 16_ ALHIV 21_ TELCF 26_ AGQVE 31_ WEKCS 36_ GIFPR 41_ DRGSQ 46_ GGSST 51_ DISVS 56_ LLAVV 61_ VSFCG 66_ LALLV 71_ VSLFV 76_ FWKLC 81_ WPCWK 86_ SKPVT 91_ SNITT 96_ LPQSI 101_ SSAPT 106_ EVFET 111_ EEKKE 116_ IKENE 121_ KPAVK 126_ AIEPA 131_ IKISH 136_ TSPDI 141_ PAEVQ 146_ TALKE 151_ HLIKH 156_ ARVQR 161_ QITEP 166_ TSSTR 171_ HSSFR 176_ RHLPR 181_ QMQVS 186_ SVDFS 191_ MGTEP 196_ VLQRG 201_ ETTTS 206_ IGRIK 211_ PELYK 216_ QKSVD 221_ SEGNQ 226_ NEDVK 231_ ICGKL 236_ NFTLQ 241_ YDYEN 246_ ELLVV 251_ KIIKA 256_ LDLPA 261_ KDFTG 266_ TSDPY 271_ VKMYL 276_ LPDRK 281_ KKFQT 286_ RVHRK 291_ TLNPL 296_ FDETF 301_ QFPVA 306_ YDQLS 311_ NRKLH 316_ FSVYD 321_ FDRFS 326_ RHDMI 331_ GEVIL 336_ DNLFE 341_ VSDLS 346_ REATV 351_ WKDIH 356_ CATTE 361_ SIDLG 366_ EIMFS 371_ LCYLP 376_ TAGRM 381_ TLTVI 386_ KCRNL 391_ KAMDI 396_ TGSSD 401_ PYVKV 406_ SLMCE 411_ GRRLK 416_ KRKTT 421_ TKKNT 426_ LNPVY 431_ NEAII 436_ FDIPP 441_ ENVDQ 446_ VSLSI 451_ AVMDY 456_ DRVGH 461_ NEVIG 466_ VCRTG 471_ LDAEG 476_ LGRDH 481_ WNEML 486_ AYHRK 491_ PITHW 496_ HPLLE 501_ LPGRA 506_ TSFDS 511_ QGSCP 516_SPKPP
1: Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. Not involved in Ca(2+)-dependent synaptic vesicle exocytosis (By similarity). Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity)