Lipase member I (LIPI) (EC 3.1.1.-) (Cancer/testis antigen 17) (CT17) (LPD lipase) (Membrane-associated phosphatidic acid-selective phospholipase A1-beta) (mPA-PLA1 beta)
1_MRVYI 6_ FLCLM 11_ CWVRS 16_ DNKRP 21_ CLEFS 26_ QLSVK 31_ DSFRD 36_ LFIPR 41_ IETIL 46_ MMYTR 51_ NNLNC 56_ AEPLF 61_ EQNNS 66_ LNVNF 71_ NTQKK 76_ TVWLI 81_ HGYRP 86_ VGSIP 91_ LWLQN 96_ FVRIL 101_ LNEED 106_ MNVIV 111_ VDWSR 116_ GATTF 121_ IYNRA 126_ VKNTR 131_ KVAVS 136_ LSVHI 141_ KNLLK 146_ HGASL 151_ DNFHF 156_ IGVSL 161_ GAHIS 166_ GFVGK 171_ IFHGQ 176_ LGRIT 181_ GLDPA 186_ GPRFS 191_ RKPPY 196_ SRLDY 201_ TDAKF 206_ VDVIH 211_ SDSNG 216_ LGIQE 221_ PLGHI 226_ DFYPN 231_ GGNKQ 236_ PGCPK 241_ SIFSG 246_ IQFIK 251_ CNHQR 256_ AVHLF 261_ MASLE 266_ TNCNF 271_ ISFPC 276_ RSYKD 281_ YKTSL 286_ CVDCD 291_ CFKEK 296_ SCPRL 301_ GYQAK 306_ LFKGV 311_ LKERM 316_ EGRPL 321_ RTTVF 326_ LDTSG 331_ TYPFC 336_ TYYFV 341_ LSIIV 346_ PDKTM 351_ MDGSF 356_ SFKLL 361_ NQLGM 366_ IEEPR 371_ LYEKN 376_ KPFYK 381_ LQEVK 386_ ILAQF 391_ YNDFV 396_ NISSI 401_ GLTYF 406_ QSSNL 411_ QCSTC 416_ TYKIQ 421_ SLMLK 426_ SLTYP 431_ ERPPL 436_ CRYNI 441_ VLKDR 446_ EEVFL 451_NPNTC
1: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG)