Dynamin-binding protein (Scaffold protein Tuba)
1_MEAGS 6_ VVRAI 11_ FDFCP 16_ SVSEE 21_ LPLFV 26_ GDIIE 31_ VLAVV 36_ DEFWL 41_ LGKKE 46_ DVTGQ 51_ FPSSF 56_ VEIVT 61_ IPSLK 66_ EGERL 71_ FVCIC 76_ EFTSQ 81_ ELDNL 86_ PLHRG 91_ DLVIL 96_ DGIPT 101_ AGWLQ 106_ GRSCW 111_ GARGF 116_ FPSSC 121_ VRELC 126_ LSSQS 131_ RQWHS 136_ QSALF 141_ QIPEY 146_ SMGQA 151_ RALMG 156_ LSAQL 161_ DEELD 166_ FREGD 171_ VITII 176_ GVPEP 181_ GWFEG 186_ ELEGR 191_ RGIFP 196_ EGFVE 201_ LLGPL 206_ RTVDE 211_ SVSSG 216_ NQDDC 221_ IVNGE 226_ VDTPV 231_ GEEEI 236_ GPDED 241_ EEEPG 246_ TYGVA 251_ LYRFQ 256_ ALEPN 261_ ELDFE 266_ VGDKI 271_ RILAT 276_ LEDGW 281_ LEGSL 286_ KGRTG 291_ IFPYR 296_ FVKLC 301_ PDTRV 306_ EETMA 311_ LPQEG 316_ SLARI 321_ PETSL 326_ DCLEN 331_ TLGVE 336_ EQRHE 341_ TSDHE 346_ AEEPD 351_ CIISE 356_ APTSP 361_ LGHLT 366_ SEYDT 371_ DRNSY 376_ QDEDT 381_ AGGPP 386_ RSPGV 391_ EWEMP 396_ LATDS 401_ PTSDP 406_ TEVVN 411_ GISSQ 416_ PQVPF 421_ HPNLQ 426_ KSQYY 431_ STVGG 436_ SHPHS 441_ EQYPD 446_ LLPLE 451_ ARTRD 456_ YASLP 461_ PKRMY 466_ SQLKT 471_ LQKPV 476_ LPLYR 481_ GSSVS 486_ ASRVV 491_ KPRQS 496_ SPQLH 501_ NLASY 506_ TKKHH 511_ TSSVY 516_ SISER 521_ LEMKP 526_ GPQAQ 531_ GLVME 536_ AATHS 541_ QGDGS 546_ TDLDS 551_ KLTQQ 556_ LIEFE 561_ KSLAG 566_ PGTEP 571_ DKILR 576_ HFSIM 581_ DFNSE 586_ KDIVR 591_ GSSKL 596_ ITEQE 601_ LPERR 606_ KALRP 611_ PPPRP 616_ CTPVS 621_ TSPHL 626_ LVDQN 631_ LKPAP 636_ PLVVR 641_ PSRPA 646_ PLPPS 651_ AQQRT 656_ NAVSP 661_ KLLSR 666_ HRPTC 671_ ETLEK 676_ EGPGH 681_ MGRSL 686_ DQTSP 691_ CPLVL 696_ VRIEE 701_ MERDL 706_ DMYSR 711_ AQEEL 716_ NLMLE 721_ EKQDE 726_ SSRAE 731_ TLEDL 736_ KFCES 741_ NIESL 746_ NMELQ 751_ QLREM 756_ TLLSS 761_ QSSSL 766_ VAPSG 771_ SVSAE 776_ NPEQR 781_ MLEKR 786_ AKVIE 791_ ELLQT 796_ ERDYI 801_ RDLEM 806_ CIERI 811_ MVPMQ 816_ QAQVP 821_ NIDFE 826_ GLFGN 831_ MQMVI 836_ KVSKQ 841_ LLAAL 846_ EISDA 851_ VGPVF 856_ LGHRD 861_ ELEGT 866_ YKIYC 871_ QNHDE 876_ AIALL 881_ EIYEK 886_ DEKIQ 891_ KHLQD 896_ SLADL 901_ KSLYN 906_ EWGCT 911_ NYINL 916_ GSFLI 921_ KPVQR 926_ VMRYP 931_ LLLME 936_ LLNST 941_ PESHP 946_ DKVPL 951_ TNAVL 956_ AVKEI 961_ NVNIN 966_ EYKRR 971_ KDLVL 976_ KYRKG 981_ DEDSL 986_ MEKIS 991_ KLNIH 996_ SIIKK 1001_ SNRVS 1006_ SHLKH 1011_ LTGFA 1016_ PQIKD 1021_ EVFEE 1026_ TEKNF 1031_ RMQER 1036_ LIKSF 1041_ IRDLS 1046_ LYLQH 1051_ IRESA 1056_ CVKVV 1061_ AAVSM 1066_ WDVCM 1071_ ERGHR 1076_ DLEQF 1081_ ERVHR 1086_ YISDQ 1091_ LFTNF 1096_ KERTE 1101_ RLVIS 1106_ PLNQL 1111_ LSMFT 1116_ GPHKL 1121_ VQKRF 1126_ DKLLD 1131_ FYNCT 1136_ ERAEK 1141_ LKDKK 1146_ TLEEL 1151_ QSARN 1156_ NYEAL 1161_ NAQLL 1166_ DELPK 1171_ FHQYA 1176_ QGLFT 1181_ NCVHG 1186_ YAEAH 1191_ CDFVH 1196_ QALEQ 1201_ LKPLL 1206_ SLLKV 1211_ AGREG 1216_ NLIAI 1221_ FHEEH 1226_ SRVLQ 1231_ QLQVF 1236_ TFFPE 1241_ SLPAT 1246_ KKPFE 1251_ RKTID 1256_ RQSAR 1261_ KPLLG 1266_ LPSYM 1271_ LQSEE 1276_ LRASL 1281_ LARYP 1286_ PEKLF 1291_ QAERN 1296_ FNAAQ 1301_ DLDVS 1306_ LLEGD 1311_ LVGVI 1316_ KKKDP 1321_ MGSQN 1326_ RWLID 1331_ NGVTK 1336_ GFVYS 1341_ SFLKP 1346_ YNPRR 1351_ SHSDA 1356_ SVGSH 1361_ SSTES 1366_ EHGSS 1371_ SPRFP 1376_ RQNSG 1381_ STLTF 1386_ NPSSM 1391_ AVSFT 1396_ SGSCQ 1401_ KQPQD 1406_ ASPPP 1411_ KECDQ 1416_ GTLSA 1421_ SLNPS 1426_ NSESS 1431_ PSRCP 1436_ SDPDS 1441_ TSQPR 1446_ SGDSA 1451_ DVARD 1456_ VKQPT 1461_ ATPRS 1466_ YRNFR 1471_ HPEIV 1476_ GYSVP 1481_ GRNGQ 1486_ SQDLV 1491_ KGCAR 1496_ TAQAP 1501_ EDRST 1506_ EPDGS 1511_ EAEGN 1516_ QVYFA 1521_ VYTFK 1526_ ARNPN 1531_ ELSVS 1536_ ANQKL 1541_ KILEF 1546_ KDVTG 1551_ NTEWW 1556_ LAEVN 1561_ GKKGY 1566_ VPSNY 1571_IRKTE
1: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells (PubMed:17015620, PubMed:19767742). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation (PubMed:20479467). Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity)