FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23)
1_MFRGP 6_ KPPIA 11_ PKPRL 16_ TAPNE 21_ WRASV 26_ YLNDS 31_ LNKCS 36_ NGRLP 41_ CVDRG 46_ LDEGP 51_ RSIPK 56_ CSESE 61_ TDEDY 66_ IVVPR 71_ VPLRE 76_ DEPKD 81_ EGSVG 86_ NKALV 91_ SPESS 96_ AEEEE 101_ EREEG 106_ GEACG 111_ LEGTG 116_ AGEDS 121_ VAPAA 126_ PGAGA 131_ LSREG 136_ EEGTD 141_ LALED 146_ EGEGC 151_ ADEPG 156_ TLEQV 161_ SRSEE 166_ EEKLV 171_ QPHRE 176_ CSLED 181_ SGPWA 186_ GEGVF 191_ QSDLL 196_ LPHIH 201_ GEDQE 206_ PPDTP 211_ GEAEE 216_ DDEEG 221_ CASTD 226_ PAGAD 231_ EGSGP 236_ DRPTE 241_ DMGQD 246_ AEDTS 251_ EEPPE 256_ KEELA 261_ GVQEA 266_ ETATD 271_ CPEVL 276_ EEGCE 281_ EATGV 286_ TGGEQ 291_ VDLSE 296_ PPDHE 301_ KKTNQ 306_ EVAAA 311_ TLEDH 316_ AQDES 321_ AEESC 326_ QIVPF 331_ ENDCM 336_ EDFVT 341_ SLTGS 346_ PYEFF 351_ PTEST 356_ SFCSE 361_ SCSPL 366_ SESAK 371_ GLESE 376_ QAPKL 381_ GLRAE 386_ ENPMV 391_ GALCG 396_ QCGSL 401_ QGGAA 406_ EGPAA 411_ PDVVV 416_ VLEEE 421_ ALDDA 426_ LANPY 431_ VMGVG 436_ LPGQA 441_ APGEG 446_ GQAAS 451_ DALGG 456_ YGSKE 461_ ELNCE 466_ AEGGL 471_ VPADR 476_ KNTST 481_ RVRPH 486_ SGKVA 491_ GYVPE 496_ TVPEE 501_ TGPEA 506_ GSSAP 511_ GIGGA 516_ AEEVG 521_ KTLLS 526_ LEGKP 531_ LEASR 536_ ALPAK 541_ PRAFT 546_ LYPRS 551_ FSVEG 556_ REIPV 561_ SVYQE 566_ PEGSG 571_ LDDHR 576_ IKRKE 581_ DNLSL 586_ SCVIG 591_ SSGSF 596_ SQRNH 601_ LPSSG 606_ TSTPS 611_ SMVDI 616_ PPPFD 621_ LACIT 626_ KKPIT 631_ KSSPS 636_ LLIES 641_ DSPDK 646_ YKKKK 651_ SSFKR 656_ FLALT 661_ FKKKT 666_ ENKLH 671_ VDVNV 676_ SSSRS 681_ SSESS 686_ YHGPS 691_ RILEV 696_ DRRSL 701_ SNSPQ 706_ LKSRT 711_ GKLRA 716_ SESPS 721_ SLIFY 726_ RDGKR 731_ KGVPF 736_ SRTVS 741_ RVESF 746_ EDRSR 751_ PPFLP 756_ LPLTK 761_ PRSIS 766_ FPSAD 771_ TSDYE 776_ NIPAM 781_ NSDYE 786_ NIQIP 791_ PRRPA 796_ RAGAF 801_ TKLFE 806_ DQSRA 811_ LSTAN 816_ ENDGY 821_ VDMSS 826_ FNAFE 831_ SKQQS 836_ ADQDA 841_ ESAYT 846_ EPYKV 851_ CPISS 856_ AAPKE 861_ DLTSD 866_ EEQRS 871_ SEEED 876_ SASRD 881_ PSVTH 886_ KVEGQ 891_ SRALV 896_ IAQEL 901_ LSSEK 906_ AYVEM 911_ LQHLN 916_ LDFHG 921_ AVMRA 926_ LDDMD 931_ HEGRD 936_ TLARE 941_ ELRQG 946_ LSELP 951_ AIHDL 956_ HQGIL 961_ EELEE 966_ RLSNW 971_ ESQQK 976_ VADVF 981_ LAREQ 986_ GFDHH 991_ ATHIL 996_ QFDRY 1001_ LGLLS 1006_ ENCLH 1011_ SPRLA 1016_ AAVRE 1021_ FEQSV 1026_ QGGSQ 1031_ TAKHR 1036_ LLRVV 1041_ QRLFQ 1046_ YQVLL 1051_ TDYLN 1056_ NLCPD 1061_ SAEYD 1066_ NTQGA 1071_ LSLIS 1076_ KVTDR 1081_ ANDSM 1086_ EQGEN 1091_ LQKLV 1096_ HIEHS 1101_ VRGQG 1106_ DLLQP 1111_ GREFL 1116_ KEGTL 1121_ MKVTG 1126_ KNRRP 1131_ RHLFL 1136_ MNDVL 1141_ LYTYP 1146_ QKDGK 1151_ YRLKN 1156_ TLAVA 1161_ NMKVS 1166_ RPVME 1171_ KVPYA 1176_ LKIET 1181_ SESCL 1186_ MLSAS 1191_ SCAER 1196_ DEWYG 1201_ CLSRA 1206_ LPEDY 1211_ KAQAL 1216_ AAFHH 1221_ SVEIR 1226_ ERLGV 1231_ SLGER 1236_ PPTLV 1241_ PVTHV 1246_ MMCMN 1251_ CGCDF 1256_ SLTLR 1261_ RHHCH 1266_ ACGKI 1271_ VCRNC 1276_ SRNKY 1281_ PLKYL 1286_ KDRMA 1291_ KVCDG 1296_ CFGEL 1301_ KKRGR 1306_ AVPGL 1311_ MRERP 1316_ VSMSF 1321_ PLSSP 1326_ RFSGS 1331_ AFSSV 1336_ FQSIN 1341_ PSTFK 1346_ KQKKV 1351_ PSALT 1356_ EVAAS 1361_ GEGSA 1366_ ISGYL 1371_ SRCKR 1376_ GKRHW 1381_ KKLWF 1386_ VIKGK 1391_ VLYTY 1396_ MASED 1401_ KVALE 1406_ SMPLL 1411_ GFTIA 1416_ PEKEE 1421_ GSSEV 1426_ GPIFH 1431_ LYHKK 1436_ TLFYS 1441_ FKAED 1446_ TNSAQ 1451_ RWIEA 1456_MEDAS
1: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape