Gene name: BICDL1

Uniprot entry:

Q6ZP65

Protein names:

BICD family-like cargo adapter 1 (Bicaudal D-related protein 1) (BICD-related protein 1) (BICDR-1) (Coiled-coil domain-containing protein 64A) (CCDC64A)

Protein sequence:

1_MSAFC 6_ LGLVG 11_ RASAP 16_ AEPDS 21_ ACCME 26_ LPAAA 31_ GDAVR 36_ SPAAA 41_ AALIF 46_ PGGSG 51_ ELELA 56_ LEEEL 61_ ALLAA 66_ GERPS 71_ DPGEH 76_ PQAEP 81_ GSLAE 86_ GAGPQ 91_ PPPSQ 96_ DPELL 101_ SVIRQ 106_ KEKDL 111_ VLAAR 116_ LGKAL 121_ LERNQ 126_ DMSRQ 131_ YEQMH 136_ KELTD 141_ KLEHL 146_ EQEKH 151_ ELRRR 156_ FENRE 161_ GEWEG 166_ RVSEL 171_ ESDVK 176_ QLQDE 181_ LERQQ 186_ IHLRE 191_ ADREK 196_ SRAVQ 201_ ELSEQ 206_ NQRLL 211_ DQLSR 216_ ASEVE 221_ RQLSM 226_ QVHAL 231_ REDFR 236_ EKNSS 241_ TNQHI 246_ IRLES 251_ LQAEI 256_ KMLSD 261_ RKREL 266_ EHRLS 271_ ATLEE 276_ NDLLQ 281_ GTVEE 286_ LQDRV 291_ LILER 296_ QGHDK 301_ DLQLH 306_ QSQLE 311_ LQEVR 316_ LSCRQ 321_ LQVKV 326_ EELTE 331_ ERSLQ 336_ SSAAT 341_ STSLL 346_ SEIEQ 351_ SMEAE 356_ ELEQE 361_ REQLR 366_ LQLWE 371_ AYCQV 376_ RYLCS 381_ HLRGN 386_ DSADS 391_ AVSTD 396_ SSMDE 401_ SSETS 406_ SAKDV 411_ PAGSL 416_ RTALN 421_ ELKRL 426_ IQSIV 431_ DGMEP 436_ TVTLL 441_ SVEMT 446_ ALKEE 451_ RDRLR 456_ VTSED 461_ KEPKE 466_ QLQKA 471_ IRDRD 476_ EAIAK 481_ KNAVE 486_ LELAK 491_ CRMDM 496_ MSLNS 501_ QLLDA 506_ IQQKL 511_ NLSQQ 516_ LEAWQ 521_ DDMHR 526_ VIDRQ 531_ LMDTH 536_ LKERS 541_ QPAAA 546_ LCRGH 551_ SAGRG 556_ DEPSI 561_ AEGKR 566_LFSFF

Protein annotations

Protein functions:

1: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor. Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis