RNA-binding protein with multiple splicing 2 (RNA binding protein, mRNA processing factor 2)
1_MSNLK 6_ PDGEH 11_ GGSTG 16_ TGSGA 21_ GSGGA 26_ LEEEV 31_ RTLFV 36_ SGLPV 41_ DIKPR 46_ ELYLL 51_ FRPFK 56_ GYEGS 61_ LIKLT 66_ ARQPV 71_ GFVIF 76_ DSRAG 81_ AEAAK 86_ NALNG 91_ IRFDP 96_ ENPQT 101_ LRLEF 106_ AKANT 111_ KMAKS 116_ KLMAT 121_ PNPSN 126_ VHPAL 131_ GAHFI 136_ ARDPY 141_ DLMGA 146_ ALIPA 151_ SPEAW 156_ APYPL 161_ YTTEL 166_ TPAIS 171_ HAAFT 176_ YPTAT 181_ AAAAA 186_ LHAQV 191_ RWYPS 196_ SDTTQ 201_QGWKY
1: RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (PubMed:25064856). Binds NOG mRNA, the major inhibitor of the bone morphogenetic protein (BMP) pathway. Mediates an increase of NOG mRNA levels, thereby contributing to the negative regulation of BMP signaling pathway and promoting reversible dedifferentiation and proliferation of smooth muscle cells (By similarity). Acts as a pre-mRNA alternative splicing regulator (By similarity). Mediates ACTN1 and FLNB alternative splicing (By similarity). Likely binds to mRNA tandem CAC trinucleotide or CA dinucleotide motifs (PubMed:24860013)