Regulator of G-protein signaling 9-binding protein (RGS9-anchoring protein)
1_MAREE 6_ CKALL 11_ DGLNK 16_ TTACY 21_ HHLVL 26_ TVGGS 31_ ADSQN 36_ LRQEL 41_ QKTRQ 46_ KAQEL 51_ AVSTC 56_ ARLTA 61_ VLRDR 66_ GLAAD 71_ ERAEF 76_ ERLWV 81_ AFSGC 86_ LDLLE 91_ ADMRR 96_ ALELG 101_ AAFPL 106_ HAPRR 111_ PLVRT 116_ GVAGA 121_ SSGVA 126_ ARALS 131_ TRSLR 136_ LEAEG 141_ DFDVA 146_ DLREL 151_ EREVL 156_ QVGEM 161_ IDNME 166_ MKVNV 171_ PRWTV 176_ QARQA 181_ AGAEL 186_ LSTVS 191_ AGPSS 196_ VVSLQ 201_ ERGGG 206_ CDPRK 211_ ALAAI 216_ LFGAV 221_ LLAAV 226_ALAVC
1: Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity)