Protein shisa-6
1_MALRR 6_ LLLLL 11_ LLSLE 16_ SLDLL 21_ PSVHG 26_ ARGRA 31_ ANRTL 36_ SAGGA 41_ AVGGR 46_ RAGGA 51_ LARGG 56_ RELNG 61_ TARAP 66_ GIPEA 71_ GSRRG 76_ QPAAA 81_ VAAAA 86_ SAAVT 91_ YETCW 96_ GYYDV 101_ SGQYD 106_ KEFEC 111_ NNSES 116_ GYLYC 121_ CGTCY 126_ YRFCC 131_ KKRHE 136_ KLDQR 141_ QCTNY 146_ QSPVW 151_ VQTPS 156_ TKVVS 161_ PGPEN 166_ KYDPE 171_ KDKTN 176_ FTVYI 181_ TCGVI 186_ AFVIV 191_ AGVFA 196_ KVSYD 201_ KAHRP 206_ PREMN 211_ IHRAL 216_ ADILR 221_ QQGPI 226_ PIAHC 231_ ERETI 236_ SAIDT 241_ SPKEN 246_ TPVRS 251_ SSKNH 256_ YTPVR 261_ TAKQT 266_ PEKPR 271_ MNNIL 276_ TSATE 281_ PYDLS 286_ FSRSF 291_ QNLAH 296_ LPPSY 301_ ESAVK 306_ TNPSK 311_ YSSLK 316_ RLTDK 321_ EADEY 326_ YMRRR 331_ HLPDL 336_ AARGT 341_ LPLNV 346_ IQMSQ 351_ QKPLP 356_ RERPR 361_ RPIRA 366_ MSQDR 371_ VLSPD 376_ RGLPD 381_ EFSMP 386_ YDRIL 391_ SDEQL 396_ LSTER 401_ LHSQD 406_ PLLSP 411_ ERTAF 416_ PEQSL 421_ SRAIS 426_ HTDVF 431_ VSTPV 436_ LDRYR 441_ MSKMH 446_ SHPSA 451_ SNNSY 456_ ATLGQ 461_ SQTAA 466_ KRHAF 471_ ASRRH 476_ NTVEQ 481_ LHYIP 486_ GHHTC 491_YTASK
1: Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses. Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway