Gene name: PAQR9

Uniprot entry:

Q6ZVX9

Protein names:

Membrane progestin receptor epsilon (mPR epsilon) (Membrane progesterone P4 receptor epsilon) (Membrane progesterone receptor epsilon) (Progesterone and adipoQ receptor family member 9) (Progestin and adipoQ receptor family member 9) (Progestin and adipoQ receptor family member IX)

Protein sequence:

1_MPRRL 6_ QPRGA 11_ GTKGP 16_ PAPAP 21_ AASGA 26_ ARNSH 31_ SAASR 36_ DPPAS 41_ AKPLL 46_ RWDEV 51_ PDDFV 56_ ECFIL 61_ SGYRR 66_ LPCTA 71_ QECLA 76_ SVLKP 81_ TNETL 86_ NFWTH 91_ FIPLL 96_ LFLSK 101_ FCRLF 106_ FLSGG 111_ DVPFH 116_ HPWLL 121_ PLWCY 126_ ASGVL 131_ LTFAM 136_ SCTAH 141_ VFSCL 146_ SLRLR 151_ AAFFY 156_ LDYAS 161_ ISYYG 166_ FGSTV 171_ AYYYY 176_ LLPGL 181_ SLLDA 186_ RVMTP 191_ YLQQR 196_ LGWHV 201_ DCTRL 206_ IAAYR 211_ ALVLP 216_ VAFVL 221_ AVACT 226_ VACCK 231_ SRTDW 236_ CTYPF 241_ ALRTF 246_ VFVMP 251_ LSMAC 256_ PIMLE 261_ SWLFD 266_ LRGEN 271_ PTLFV 276_ HFYRR 281_ YFWLV 286_ VAAFF 291_ NVSKI 296_ PERIQ 301_ PGLFD 306_ IIGHS 311_ HQLFH 316_ IFTFL 321_ SIYDQ 326_ VYYVE 331_ EGLRQ 336_ FLQAP 341_ PAAPT 346_ FSGTV 351_ GYMLL 356_ LVVCL 361_ GLVIR 366_ KFLNS 371_SEFCS

Protein annotations

Protein functions:

1: Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23161870, PubMed:23763432). Seems to act through a G(s) mediated pathway (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870)