Centromere protein U (CENP-U) (Centromere protein of 50 kDa) (CENP-50) (Interphase centromere complex protein 24) (KSHV latent nuclear antigen-interacting protein 1) (MLF1-interacting protein) (Polo-box-interacting protein 1)
1_MAPRG 6_ RRRPR 11_ PHRSE 16_ GARRS 21_ KNTLE 26_ RTHSM 31_ KDKAG 36_ QKCKP 41_ IDVFD 46_ FPDNS 51_ DVSSI 56_ GRLGE 61_ NEKDE 66_ ETYET 71_ FDPPL 76_ HSTAI 81_ YADEE 86_ EFSKH 91_ CGLSL 96_ SSTPP 101_ GKEAK 106_ RSSDT 111_ SGNEA 116_ SEIES 121_ VKISA 126_ KKPGR 131_ KLRPI 136_ SDDSE 141_ SIEES 146_ DTRRK 151_ VKSAE 156_ KISTQ 161_ RHEVI 166_ RTTAS 171_ SELSE 176_ KPAES 181_ VTSKK 186_ TGPLS 191_ AQPSV 196_ EKENL 201_ AIESQ 206_ SKTQK 211_ KGKIS 216_ HDKRK 221_ KSRSK 226_ AIGSD 231_ TSDIV 236_ HIWCP 241_ EGMKT 246_ SDIKE 251_ LNIVL 256_ PEFEK 261_ THLEH 266_ QQRIE 271_ SKVCK 276_ AAIAT 281_ FYVNV 286_ KEQFI 291_ KMLKE 296_ SQMLT 301_ NLKRK 306_ NAKMI 311_ SDIEK 316_ KRQRM 321_ IEVQD 326_ ELLRL 331_ EPQLK 336_ QLQTK 341_ YDELK 346_ ERKSS 351_ LRNAA 356_ YFLSN 361_ LKQLY 366_ QDYSD 371_ VQAQE 376_ PNVKE 381_ TYDSS 386_ SLPAL 391_ LFKAR 396_ TLLGA 401_ ESHLR 406_ NINHQ 411_LEKLL
1: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression