Immunoglobulin-like domain-containing receptor 2 (Angulin-3)
1_MDRVL 6_ LRWIS 11_ LFWLT 16_ AMVEG 21_ LQVTV 26_ PDKKK 31_ VAMLF 36_ QPTVL 41_ RCHFS 46_ TSSHQ 51_ PAVVQ 56_ WKFKS 61_ YCQDR 66_ MGESL 71_ GMSST 76_ RAQSL 81_ SKRNL 86_ EWDPY 91_ LDCLD 96_ SRRTV 101_ RVVAS 106_ KQGST 111_ VTLGD 116_ FYRGR 121_ EITIV 126_ HDADL 131_ QIGKL 136_ MWGDS 141_ GLYYC 146_ IITTP 151_ DDLEG 156_ KNEDS 161_ VELLV 166_ LGRTG 171_ LLADL 176_ LPSFA 181_ VEIMP 186_ EWVFV 191_ GLVLL 196_ GVFLF 201_ FVLVG 206_ ICWCQ 211_ CCPHS 216_ CCCYV 221_ RCPCC 226_ PDSCC 231_ CPQAL 236_ YEAGK 241_ AAKAG 246_ YPPSV 251_ SGVPG 256_ PYSIP 261_ SVPLG 266_ GAPSS 271_ GMLMD 276_ KPHPP 281_ PLAPS 286_ DSTGG 291_ SHSVR 296_ KGYRI 301_ QADKE 306_ RDSMK 311_ VLYYV 316_ EKELA 321_ QFDPA 326_ RRMRG 331_ RYNNT 336_ ISELS 341_ SLHEE 346_ DSNFR 351_ QSFHQ 356_ MRSKQ 361_ FPVSG 366_ DLESN 371_ PDYWS 376_ GVMGG 381_ SSGAS 386_ RGPSA 391_ MEYNK 396_ EDRES 401_ FRHSQ 406_ PRSKS 411_ EMLSR 416_ KNFAT 421_ GVPAV 426_ SMDEL 431_ AAFAD 436_ SYGQR 441_ PRRAD 446_ GNSHE 451_ ARGGS 456_ RFERS 461_ ESRAH 466_ SGFYQ 471_ DDSLE 476_ EYYGQ 481_ RSRSR 486_ EPLTD 491_ ADRGW 496_ AFSPA 501_ RRRPA 506_ EDAHL 511_ PRLVS 516_ RTPGT 521_ APKYD 526_ HSYLG 531_ SARER 536_ QARPE 541_ GASRG 546_ GSLET 551_ PSKRS 556_ AQLGP 561_ RSASY 566_ YAWSP 571_ PGTYK 576_ AGSSQ 581_ DDQED 586_ ASDDA 591_ LPPYS 596_ ELELT 601_ RGPSY 606_ RGRDL 611_ PYHSN 616_ SEKKR 621_ KKEPA 626_ KKTND 631_FPTRM
1: May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions (By similarity). Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity (PubMed:29431694). In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1 (By similarity)