Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78)
1_MVPGS 6_ EGPAR 11_ AGSVV 16_ ADVVF 21_ VIEGT 26_ ANLGP 31_ YFEGL 36_ RKHYL 41_ LPAIE 46_ YFNGG 51_ PPAET 56_ DFGGD 61_ YGGTQ 66_ YSLVV 71_ FNTVD 76_ CAPES 81_ YVQCH 86_ APTSS 91_ AYEFV 96_ TWLDG 101_ IKFMG 106_ GGGES 111_ CSLIA 116_ EGLST 121_ ALQLF 126_ DDFKK 131_ MREQI 136_ GQTHR 141_ VCLLI 146_ CNSPP 151_ YLLPA 156_ VESTT 161_ YSGCT 166_ TENLV 171_ QQIGE 176_ RGIHF 181_ SIVSP 186_ RKLPA 191_ LRLLF 196_ EKAAP 201_ PALLE 206_ PLQPP 211_ TDVSQ 216_ DPRHM 221_ VLVRG 226_ LVLPV 231_ GGGSA 236_ PGPLQ 241_ SKQPV 246_ PLPPA 251_ APSGA 256_ TLSAA 261_ PQQPL 266_ PPVPP 271_ QYQVP 276_ GNLSA 281_ AQVAA 286_ QNAVE 291_ AAKNQ 296_ KAGLG 301_ PRFSP 306_ ITPLQ 311_ QAAPG 316_ VGPPF 321_ SQAPA 326_ PQLPP 331_ GPPGA 336_ PKPPP 341_ ASQPS 346_ LVSTV 351_ APGSG 356_ LAPTA 361_ QPGAP 366_ SMAGT 371_ VAPGG 376_ VSGPS 381_ PAQLG 386_ APALG 391_ GQQSV 396_ SNKLL 401_ AWSGV 406_ LEWQE 411_ KPKPA 416_ SVDAN 421_ TKLTR 426_ SLPCQ 431_ VYVNH 436_ GENLK 441_ TEQWP 446_ QKLIM 451_ QLIPQ 456_ QLLTT 461_ LGPLF 466_ RNSRM 471_ VQFHF 476_ TNKDL 481_ ESLKG 486_ LYRIM 491_ GNGFA 496_ GCVHF 501_ PHTAP 506_ CEVRV 511_ LMLLY 516_ SSKKK 521_ IFMGL 526_ IPYDQ 531_ SGFVN 536_ GIRQV 541_ ITNHK 546_ QVQQQ 551_ KLEQQ 556_ QRGMG 561_ GQQAP 566_ PGLGP 571_ ILEDQ 576_ ARPSQ 581_ NLLQL 586_ RPPQP 591_ QPQGT 596_ VGASG 601_ ATGQP 606_ QPQGT 611_ AQPPP 616_ GAPQG 621_ PPGAA 626_ SGPPP 631_ PGPIL 636_ RPQNP 641_ GANPQ 646_ LRSLL 651_ LNPPP 656_ PQTGV 661_ PPPQA 666_ SLHHL 671_ QPPGA 676_ PALLP 681_ PPHQG 686_ LGQPQ 691_ LGPPL 696_ LHPPP 701_ AQSWP 706_ AQLPP 711_ RAPLP 716_ GQMLL 721_ SGGPR 726_ GPVPQ 731_ PGLQP 736_ SVMED 741_DILMD
1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for RARA/RXRA-mediated transcription