Testis-specific H1 histone (Haploid germ cell-specific nuclear protein 1) (Histone H1.7) (Histone H1t2)
1_MEQAL 6_ TGEAQ 11_ SRWPR 16_ RGGSG 21_ AMAEA 26_ PGPSG 31_ ESRGH 36_ SATQL 41_ PAEKT 46_ VGGPS 51_ RGCSS 56_ SVLRV 61_ SQLVL 66_ QAIST 71_ HKGLT 76_ LAALK 81_ KELRN 86_ AGYEV 91_ RRKSG 96_ RHEAP 101_ RGQAK 106_ ATLLR 111_ VSGSD 116_ AAGYF 121_ RVWKV 126_ PKPRR 131_ KPGRA 136_ RQEEG 141_ TRAPW 146_ RTPAA 151_ PRSSR 156_ RRRQP 161_ LRKAA 166_ RKARE 171_ VWRRN 176_ ARAKA 181_ KANAR 186_ ARRTR 191_ RARPR 196_ AKEPP 201_ CARAK 206_ EEAGA 211_ TAADE 216_ GRGQA 221_ VKEDT 226_ TPRSG 231_ KDKRR 236_ SSKPR 241_ EEKQE 246_PKKPA
1: Essential for normal spermatogenesis and male fertility (PubMed:16533358). Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1