Protein phosphatase Slingshot homolog 2 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 2) (SSH-2L) (hSSH-2L)
1_MALVT 6_ VQRSP 11_ TPSTT 16_ SSPCA 21_ SEADS 26_ GEEEC 31_ RSQPR 36_ SISES 41_ FLTVK 46_ GAALF 51_ LPRGN 56_ GSSTP 61_ RISHR 66_ RNKHA 71_ GDLQQ 76_ HLQAM 81_ FILLR 86_ PEDNI 91_ RLAVR 96_ LESTY 101_ QNRTR 106_ YMVVV 111_ STNGR 116_ QDTEE 121_ SIVLG 126_ MDFSS 131_ NDSST 136_ CTMGL 141_ VLPLW 146_ SDTLI 151_ HLDGD 156_ GGFSV 161_ STDNR 166_ VHIFK 171_ PVSVQ 176_ AMWSA 181_ LQSLH 186_ KACEV 191_ ARAHN 196_ YYPGS 201_ LFLTW 206_ VSYYE 211_ SHINS 216_ DQSSV 221_ NEWNA 226_ MQDVQ 231_ SHRPD 236_ SPALF 241_ TDIPT 246_ ERERT 251_ ERLIK 256_ TKLRE 261_ IMMQK 266_ DLENI 271_ TSKEI 276_ RTELE 281_ MQMVC 286_ NLREF 291_ KEFID 296_ NEMIV 301_ ILGQM 306_ DSPTQ 311_ IFEHV 316_ FLGSE 321_ WNASN 326_ LEDLQ 331_ NRGVR 336_ YILNV 341_ TREID 346_ NFFPG 351_ VFEYH 356_ NIRVY 361_ DEEAT 366_ DLLAY 371_ WNDTY 376_ KFISK 381_ AKKHG 386_ SKCLV 391_ HCKMG 396_ VSRSA 401_ STVIA 406_ YAMKE 411_ YGWNL 416_ DRAYD 421_ YVKER 426_ RTVTK 431_ PNPSF 436_ MRQLE 441_ EYQGI 446_ LLASK 451_ QRHNK 456_ LWRSH 461_ SDSDL 466_ SDHHE 471_ PICKP 476_ GLELN 481_ KKDIT 486_ TSADQ 491_ IAEVK 496_ TMESH 501_ PPIPP 506_ VFVEH 511_ MVPQD 516_ ANQKG 521_ LCTKE 526_ RMICL 531_ EFTSR 536_ EFHAG 541_ QIEDE 546_ LNLND 551_ INGCS 556_ SGCCL 561_ NESKF 566_ PLDNC 571_ HASKA 576_ LIQPG 581_ HVPEM 586_ ANKFP 591_ DLTVE 596_ DLETD 601_ ALKAD 606_ MNVHL 611_ LPMEE 616_ LTSPL 621_ KDPPM 626_ SPDPE 631_ SPSPQ 636_ PSCQT 641_ EISDF 646_ STDRI 651_ DFFSA 656_ LEKFV 661_ ELSQE 666_ TRSRS 671_ FSHSR 676_ MEELG 681_ GGRNE 686_ SCRLS 691_ VVEVA 696_ PSKVT 701_ ADDQR 706_ SSSLS 711_ NTPHA 716_ SEESS 721_ MDEEQ 726_ SKAIS 731_ ELVSP 736_ DIFMQ 741_ SHSEN 746_ AISVK 751_ EIVTE 756_ IESIS 761_ QGVGQ 766_ IQLKG 771_ DILPN 776_ PCHTP 781_ KKNSI 786_ HELLL 791_ ERAQT 796_ PENKP 801_ GHMEQ 806_ DEDSC 811_ TAQPE 816_ LAKDS 821_ GMCNP 826_ EGCLT 831_ THSSI 836_ ADLEE 841_ GEPAE 846_ GEQEL 851_ QGSGM 856_ HPGAK 861_ WYPGS 866_ VRRAT 871_ LEFEE 876_ RLRQE 881_ QEHHG 886_ AAPTC 891_ TSLST 896_ RKNSK 901_ NDSSV 906_ ADLAP 911_ KGKSD 916_ EAPPE 921_ HSFVL 926_ KEPEM 931_ SKGKG 936_ KYSGS 941_ EAGSL 946_ SHSEQ 951_ NATVP 956_ APRVL 961_ EFDHL 966_ PDPQE 971_ GPGSD 976_ TGTQQ 981_ EGVLK 986_ DLRTV 991_ IPYQE 996_ SETQA 1001_ VPLPL 1006_ PKRVE 1011_ IIEYT 1016_ HIVTS 1021_ PNHTG 1026_ PGSEI 1031_ ATSEK 1036_ SGEQG 1041_ LRKVN 1046_ MEKSV 1051_ TVLCT 1056_ LDENL 1061_ NRTLD 1066_ PNQVS 1071_ LHPQV 1076_ LPLPH 1081_ SSSPE 1086_ HNRPT 1091_ DHPTS 1096_ ILSSP 1101_ EDRGS 1106_ SLSTA 1111_ LETAA 1116_ PFVSH 1121_ TTHLL 1126_ SASLD 1131_ YLHPQ 1136_ TMVHL 1141_ EGFTE 1146_ QSSTT 1151_ DEPSA 1156_ EQVSW 1161_ EESQE 1166_ SPLSS 1171_ GSEVP 1176_ YKDSQ 1181_ LSSAD 1186_ LSLIS 1191_ KLGDN 1196_ TGELQ 1201_ EKMDP 1206_ LPVAC 1211_ RLPHS 1216_ SSSEN 1221_ IKSLS 1226_ HSPGV 1231_ VKERA 1236_ KEIES 1241_ RVVFQ 1246_ AGLTK 1251_ PSQMR 1256_ RSASL 1261_ AKLGY 1266_ LDLCK 1271_ DCLPE 1276_ REPAS 1281_ CESPH 1286_ LKLLQ 1291_ PFLRT 1296_ DSGMH 1301_ AMEDQ 1306_ ESLEN 1311_ PGAPH 1316_ NPEPT 1321_ KSFVE 1326_ QLTTT 1331_ ECIVQ 1336_ SKPVE 1341_ RPLVQ 1346_ YAKEF 1351_ GSSQQ 1356_ YLLPR 1361_ AGLEL 1366_ TSSEG 1371_ GLPVL 1376_ QTQGL 1381_ QCACP 1386_ APGLA 1391_ VAPRQ 1396_ QHGRT 1401_ HPLRR 1406_ LKKAN 1411_ DKKRT 1416_TNPFY
1: Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein (PubMed:11832213). Required for spermatogenesis (By similarity). Involved in acrosome biogenesis, probably by regulating cofilin-mediated actin cytoskeleton remodeling during proacrosomal vesicle fusion and/or Golgi to perinuclear vesicle trafficking (By similarity)