Synaptic vesicle glycoprotein 2A
1_MEEGF 6_ RDRAA 11_ FIRGA 16_ KDIAK 21_ EVKKH 26_ AAKKV 31_ VKGLD 36_ RVQDE 41_ YSRRS 46_ YSRFE 51_ EEDDD 56_ DDFPA 61_ PSDGY 66_ YRGEG 71_ TQDEE 76_ EGGAS 81_ SDATE 86_ GHDED 91_ DEIYE 96_ GEYQG 101_ IPRAE 106_ SGGKG 111_ ERMAD 116_ GAPLA 121_ GVRGG 126_ LSDGE 131_ GPPGG 136_ RGEAQ 141_ RRKER 146_ EELAQ 151_ QYEAI 156_ LRECG 161_ HGRFQ 166_ WTLYF 171_ VLGLA 176_ LMADG 181_ VEVFV 186_ VGFVL 191_ PSAEK 196_ DMCLS 201_ DSNKG 206_ MLGLI 211_ VYLGM 216_ MVGAF 221_ LWGGL 226_ ADRLG 231_ RRQCL 236_ LISLS 241_ VNSVF 246_ AFFSS 251_ FVQGY 256_ GTFLF 261_ CRLLS 266_ GVGIG 271_ GSIPI 276_ VFSYF 281_ SEFLA 286_ QEKRG 291_ EHLSW 296_ LCMFW 301_ MIGGV 306_ YAAAM 311_ AWAII 316_ PHYGW 321_ SFQMG 326_ SAYQF 331_ HSWRV 336_ FVLVC 341_ AFPSV 346_ FAIGA 351_ LTTQP 356_ ESPRF 361_ FLENG 366_ KHDEA 371_ WMVLK 376_ QVHDT 381_ NMRAK 386_ GHPER 391_ VFSVT 396_ HIKTI 401_ HQEDE 406_ LIEIQ 411_ SDTGT 416_ WYQRW 421_ GVRAL 426_ SLGGQ 431_ VWGNF 436_ LSCFG 441_ PEYRR 446_ ITLMM 451_ MGVWF 456_ TMSFS 461_ YYGLT 466_ VWFPD 471_ MIRHL 476_ QAVDY 481_ ASRTK 486_ VFPGE 491_ RVEHV 496_ TFNFT 501_ LENQI 506_ HRGGQ 511_ YFNDK 516_ FIGLR 521_ LKSVS 526_ FEDSL 531_ FEECY 536_ FEDVT 541_ SSNTF 546_ FRNCT 551_ FINTV 556_ FYNTD 561_ LFEYK 566_ FVNSR 571_ LINST 576_ FLHNK 581_ EGCPL 586_ DVTGT 591_ GEGAY 596_ MVYFV 601_ SFLGT 606_ LAVLP 611_ GNIVS 616_ ALLMD 621_ KIGRL 626_ RMLAG 631_ SSVMS 636_ CVSCF 641_ FLSFG 646_ NSESA 651_ MIALL 656_ CLFGG 661_ VSIAS 666_ WNALD 671_ VLTVE 676_ LYPSD 681_ KRTTA 686_ FGFLN 691_ ALCKL 696_ AAVLG 701_ ISIFT 706_ SFVGI 711_ TKAAP 716_ ILFAS 721_ AALAL 726_ GSSLA 731_ LKLPE 736_TRGQV
1: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)
2: (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction (PubMed:29649119). Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1