Centromere protein Q (CENP-Q)
1_MSGKA 6_ NASKK 11_ NAQQL 16_ KRNPK 21_ RKKDN 26_ EEVVL 31_ SENKV 36_ RNTVK 41_ KNKNH 46_ LKDLS 51_ SEGQT 56_ KHTNL 61_ KHGKT 66_ AASKR 71_ KTWQP 76_ LSKST 81_ RDHLQ 86_ TMMES 91_ VIMTI 96_ LSNSI 101_ KEKEE 106_ IQYHL 111_ NFLKK 116_ RLLQQ 121_ CETLK 126_ VPPKK 131_ MEDLT 136_ NVSSL 141_ LNMER 146_ ARDKA 151_ NEEGL 156_ ALLQE 161_ EIDKM 166_ VETTE 171_ LMTGN 176_ IQSLK 181_ NKIQI 186_ LASEV 191_ EEEEE 196_ RVKQM 201_ HQINS 206_ SGVLS 211_ LPELS 216_ QKTLK 221_ APTLQ 226_ KEILA 231_ LIPNQ 236_ NALLK 241_ DLDIL 246_ HNSSQ 251_ MKSMS 256_ TFIEE 261_AYKKL
1: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (PubMed:16622420). Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores (PubMed:25395579)