Probable proline--tRNA ligase, mitochondrial (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)
1_MEGLL 6_ TRCRA 11_ LPALA 16_ TCSRQ 21_ LSGYV 26_ PCRFH 31_ HCAPR 36_ RGRRL 41_ LLSRV 46_ FQPQN 51_ LREDR 56_ VLSLQ 61_ DKSDD 66_ LTCKS 71_ QRLML 76_ QVGLI 81_ YPASP 86_ GCYHL 91_ LPYTV 96_ RAMEK 101_ LVRVI 106_ DQEMQ 111_ AIGGQ 116_ KVNMP 121_ SLSPA 126_ ELWQA 131_ TNRWD 136_ LMGKE 141_ LLRLR 146_ DRHGK 151_ EYCLG 156_ PTHEE 161_ AITAL 166_ IASQK 171_ KLSYK 176_ QLPFL 181_ LYQVT 186_ RKFRD 191_ EPRPR 196_ FGLLR 201_ GREFY 206_ MKDMY 211_ TFDSS 216_ PEAAQ 221_ QTYSL 226_ VCDAY 231_ CSLFN 236_ KLGLP 241_ FVKVQ 246_ ADVGT 251_ IGGTV 256_ SHEFQ 261_ LPVDI 266_ GEDRL 271_ AICPR 276_ CSFSA 281_ NMETL 286_ DLSQM 291_ NCPAC 296_ QGPLT 301_ KTKGI 306_ EVGHT 311_ FYLGT 316_ KYSSI 321_ FNAQF 326_ TNVCG 331_ KPTLA 336_ EMGCY 341_ GLGVT 346_ RILAA 351_ AIEVL 356_ STEDC 361_ VRWPS 366_ LLAPY 371_ QACLI 376_ PPKKG 381_ SKEQA 386_ ASELI 391_ GQLYD 396_ HITEA 401_ VPQLH 406_ GEVLL 411_ DDRTH 416_ LTIGN 421_ RLKDA 426_ NKFGY 431_ PFVII 436_ AGKRA 441_ LEDPA 446_ HFEVW 451_ CQNTG 456_ EVAFL 461_ TKDGV 466_MDLLT
1: Mitochondrial aminoacyl-tRNA synthetase that catalyzes the specific attachment of the proline amino acid (aa) to the homologous transfer RNA (tRNA), further participating in protein synthesis. The reaction occurs in a two steps: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro)