Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)
1_MAAQV 6_ TLEDA 11_ LSNVD 16_ LLEEL 21_ PLPDQ 26_ QPCIE 31_ PPPSS 36_ LLYQP 41_ NFNTN 46_ FEDRN 51_ AFVTG 56_ IARYI 61_ EQATV 66_ HSSMN 71_ EMLEE 76_ GQEYA 81_ VMLYT 86_ WRSCS 91_ RAIPQ 96_ VKCNE 101_ QPNRV 106_ EIYEK 111_ TVEVL 116_ EPEVT 121_ KLMNF 126_ MYFQR 131_ NAIER 136_ FCGEV 141_ RRLCH 146_ AERRK 151_ DFVSE 156_ AYLIT 161_ LGKFI 166_ NMFAV 171_ LDELK 176_ NMKCS 181_ VKNDH 186_ SAYKR 191_ AAQFL 196_ RKMAD 201_ PQSIQ 206_ ESQNL 211_ SMFLA 216_ NHNKI 221_ TQSLQ 226_ QQLEV 231_ ISGYE 236_ ELLAD 241_ IVNLC 246_ VDYYE 251_ NRMYL 256_ TPSEK 261_ HMLLK 266_ VMGFG 271_ LYLMD 276_ GSVSN 281_ IYKLD 286_ AKKRI 291_ NLSKI 296_ DKYFK 301_ QLQVV 306_ PLFGD 311_ MQIEL 316_ ARYIK 321_ TSAHY 326_ EENKS 331_ RWTCT 336_ SSGSS 341_ PQYNI 346_ CEQMI 351_ QIRED 356_ HMRFI 361_ SELAR 366_ YSNSE 371_ VVTGS 376_ GRQEA 381_ QKTDA 386_ EYRKL 391_ FDLAL 396_ QGLQL 401_ LSQWS 406_ AHVME 411_ VYSWK 416_ LVHPT 421_ DKYSN 426_ KDCPD 431_ SAEEY 436_ ERATR 441_ YNYTS 446_ EEKFA 451_ LVEVI 456_ AMIKG 461_ LQVLM 466_ GRMES 471_ VFNHA 476_ IRHTV 481_ YAALQ 486_ DFSQV 491_ TLREP 496_ LRQAI 501_ KKKKN 506_ VIQSV 511_ LQAIR 516_ KTVCD 521_ WETGH 526_ EPFND 531_ PALRG 536_ EKDPK 541_ SGFDI 546_ KVPRR 551_ AVGPS 556_ STQLY 561_ MVRTM 566_ LESLI 571_ ADKSG 576_ SKKTL 581_ RSSLE 586_ GPTIL 591_ DIEKF 596_ HRESF 601_ FYTHL 606_ INFSE 611_ TLQQC 616_ CDLSQ 621_ LWFRE 626_ FFLEL 631_ TMGRR 636_ IQFPI 641_ EMSMP 646_ WILTD 651_ HILET 656_ KEASM 661_ MEYVL 666_ YSLDL 671_ YNDSA 676_ HYALT 681_ RFNKQ 686_ FLYDE 691_ IEAEV 696_ NLCFD 701_ QFVYK 706_ LADQI 711_ FAYYK 716_ VMAGS 721_ LLLDK 726_ RLRSE 731_ CKNQG 736_ ATIHL 741_ PPSNR 746_ YETLL 751_ KQRHV 756_ QLLGR 761_ SIDLN 766_ RLITQ 771_ RVSAA 776_ MYKSL 781_ ELAIG 786_ RFESE 791_ DLTSI 796_ VELDG 801_ LLEIN 806_ RMTHK 811_ LLSRY 816_ LTLDG 821_ FDAMF 826_ REANH 831_ NVSAP 836_ YGRIT 841_ LHVFW 846_ ELNYD 851_ FLPNY 856_ CYNGS 861_ TNRFV 866_ RTVLP 871_ FSQEF 876_ QRDKQ 881_ PNAQP 886_ QYLHG 891_ SKALN 896_ LAYSS 901_ IYGSY 906_ RNFVG 911_ PPHFQ 916_ VICRL 921_ LGYQG 926_ IAVVM 931_ EELLK 936_ VVKSL 941_ LQGTI 946_ LQYVK 951_ TLMEV 956_ MPKIC 961_ RLPRH 966_ EYGSP 971_ GILEF 976_ FHHQL 981_ KDIVE 986_ YAELK 991_ TVCFQ 996_ NLREV 1001_ GNAIL 1006_ FCLLI 1011_ EQSLS 1016_ LEEVC 1021_ DLLHA 1026_ APFQN 1031_ ILPRV 1036_ HVKEG 1041_ ERLDA 1046_ KMKRL 1051_ ESKYA 1056_ PLHLV 1061_ PLIER 1066_ LGTPQ 1071_ QIAIA 1076_ REGDL 1081_ LTKER 1086_ LCCGL 1091_ SMFEV 1096_ ILTRI 1101_ RSFLD 1106_ DPIWR 1111_ GPLPS 1116_ NGVMH 1121_ VDECV 1126_ EFHRL 1131_ WSAMQ 1136_ FVYCI 1141_ PVGTH 1146_ EFTVE 1151_ QCFGD 1156_ GLHWA 1161_ GCMII 1166_ VLLGQ 1171_ QRRFA 1176_ VLDFC 1181_ YHLLK 1186_ VQKHD 1191_ GKDEI 1196_ IKNVP 1201_ LKKMV 1206_ ERIRK 1211_ FQILN 1216_ DEIIT 1221_ ILDKY 1226_ LKSGD 1231_ GEGTP 1236_ VEHVR 1241_ CFQPP 1246_IHQSL
1: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers