Gene name: ADM2

Uniprot entry:

Q7Z4H4

Protein names:

Protein ADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)]

Protein sequence:

1_MARIP 6_ TAALG 11_ CISLL 16_ CLQLP 21_ GSLSR 26_ SLGGD 31_ PRPVK 36_ PREPP 41_ ARSPS 46_ SSLQP 51_ RHPAP 56_ RPVVW 61_ KLHRA 66_ LQAQR 71_ GAGLA 76_ PVMGQ 81_ PLRDG 86_ GRQHS 91_ GPRRH 96_ SGPRR 101_ TQAQL 106_ LRVGC 111_ VLGTC 116_ QVQNL 121_ SHRLW 126_ QLMGP 131_ AGRQD 136_ SAPVD 141_PSSPH

Protein annotations

Protein functions:

1: Intermedin/ADM2 is a peptide hormone that plays a role as physiological regulator of gastrointestinal and cardiovascular bioactivities mediated by the CALCRL-RAMPs receptor complexes (PubMed:14615490). Activates the cAMP-dependent pathway through interaction with CALCRL-RAMP3 receptor complex (PubMed:14615490)