Gene name: REC114

Uniprot entry:

Q7Z4M0

Protein names:

Meiotic recombination protein REC114

Protein sequence:

1_MAEAG 6_ KVPLS 11_ LGLTG 16_ GEAAE 21_ WPLQR 26_ YARCI 31_ PSNTR 36_ DPPGP 41_ CLEAG 46_ TAPCP 51_ TWKVF 56_ DSNEE 61_ SGYLV 66_ LTIVI 71_ SGHFF 76_ IFQGQ 81_ TLLEG 86_ FSLIG 91_ SKDWL 96_ KIVRR 101_ VDCLL 106_ FGTTI 111_ KDKSR 116_ LFRVQ 121_ FSGES 126_ KEQAL 131_ EHCCS 136_ CVQKL 141_ AQYIT 146_ VQVPD 151_ GNIQE 156_ LQLIP 161_ GPPRA 166_ TESQG 171_ KDSAK 176_ SVPRQ 181_ PGSHQ 186_ HSEQQ 191_ QVCVT 196_ AGTGA 201_ PDGRT 206_ SLTQL 211_ AQTLL 216_ ASEEL 221_ PHVYE 226_ QSAWG 231_ AEELG 236_ PFLRL 241_ CLMDQ 246_ NFPAF 251_ VEEVE 256_ KELKK 261_LAGLR

Protein annotations

Protein functions:

1: Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination (PubMed:38148155). Probably acts by forming a complex with IHO1 and MEI4, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis (By similarity). Required for spermatogenesis (PubMed:38148155). Required for oogenesis