Protein RIC-3 (Resistant to inhibitor of cholinesterase 3)
1_MAYST 6_ VQRVA 11_ LASGL 16_ VLALS 21_ LLLPK 26_ AFLSR 31_ GKRQE 36_ PPPTP 41_ EGKLG 46_ RFPPM 51_ MHHHQ 56_ APSDG 61_ QTPGA 66_ RFQRS 71_ HLAEA 76_ FAKAK 81_ GSGGG 86_ AGGGG 91_ SGRGL 96_ MGQII 101_ PIYGF 106_ GIFLY 111_ ILYIL 116_ FKLSK 121_ GKTTA 126_ EDGKC 131_ YTAMP 136_ GNTHR 141_ KITSF 146_ ELAQL 151_ QEKLK 156_ ETEAA 161_ MEKLI 166_ NRVGP 171_ NGESR 176_ AQTVT 181_ SDQEK 186_ RLLHQ 191_ LREIT 196_ RVMKE 201_ GKFID 206_ RFSPE 211_ KEAEE 216_ APYME 221_ DWEGY 226_ PEETY 231_ PIYDL 236_ SDCIK 241_ RRQET 246_ ILVDY 251_ PDPKE 256_ LSAEE 261_ IAERM 266_ GMIEE 271_ EESDH 276_ LGWES 281_ LPTDP 286_ RAQED 291_ NSVTS 296_ CDPKP 301_ ETCSC 306_ CFHED 311_ EDPAV 316_ LAENA 321_ GFSAD 326_ SYPEQ 331_ EETTK 336_ EEWSQ 341_ DFKDE 346_ GLGIS 351_ TDKAY 356_ TGSML 361_RKRNP
1: Molecular chaperone which facilitates proper subunit assembly and surface trafficking of alpha-7 (CHRNA7) and alpha-8 (CHRNA8) nicotinic acetylcholine receptors (PubMed:12821669, PubMed:15504725, PubMed:16120769, PubMed:18691158, PubMed:32204458). May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4