17-beta-hydroxysteroid dehydrogenase 13 (17-beta-HSD 13) (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 16C member 3) (Short-chain dehydrogenase/reductase 9)
1_MNIIL 6_ EILLL 11_ LITII 16_ YSYLE 21_ SLVKF 26_ FIPQR 31_ RKSVA 36_ GEIVL 41_ ITGAG 46_ HGIGR 51_ QTTYE 56_ FAKRQ 61_ SILVL 66_ WDINK 71_ RGVEE 76_ TAAEC 81_ RKLGV 86_ TAHAY 91_ VVDCS 96_ NREEI 101_ YRSLN 106_ QVKKE 111_ VGDVT 116_ IVVNN 121_ AGTVY 126_ PADLL 131_ STKDE 136_ EITKT 141_ FEVNI 146_ LGHFW 151_ ITKAL 156_ LPSMM 161_ ERNHG 166_ HIVTV 171_ ASVCG 176_ HEGIP 181_ YLIPY 186_ CSSKF 191_ AAVGF 196_ HRGLT 201_ SELQA 206_ LGKTG 211_ IKTSC 216_ LCPVF 221_ VNTGF 226_ TKNPS 231_ TRLWP 236_ VLETD 241_ EVVRS 246_ LIDGI 251_ LTNKK 256_ MIFVP 261_ SYINI 266_ FLRLQ 271_ KFLPE 276_ RASAI 281_ LNRMQ 286_ NIQFE 291_AVVGH
1: Plays a pivotal role in hepatic lipid metabolism (PubMed:29562163). In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4 (PubMed:29562163, PubMed:30415504, PubMed:32973038)
2: Has retinol/retinal dehydrogenase activity in vitro
3: Does not have retinol/retinal dehydrogenase activity in vitro