Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3)
1_MAASS 6_ SEISE 11_ MKGVE 16_ ESPKV 21_ PGEGP 26_ GHSEA 31_ ETGPP 36_ QVLAG 41_ VPDQP 46_ EAPQP 51_ GPNTT 56_ AAPVD 61_ SGPKA 66_ GLAPE 71_ TTETP 76_ AGASE 81_ TAQAT 86_ DLSLS 91_ PGGES 96_ KANCS 101_ PEDPC 106_ QETVS 111_ KPEVS 116_ KEATA 121_ DQGSR 126_ LESAA 131_ PPEPA 136_ PEPAP 141_ QPDPR 146_ PDSQP 151_ TPKPA 156_ LQPEL 161_ PTQED 166_ PTPEI 171_ LSESV 176_ GEKQE 181_ NGAVV 186_ PLQAG 191_ DGEEG 196_ PAPEP 201_ HSPPS 206_ KKSPP 211_ ANGAP 216_ PRVLQ 221_ QLVEE 226_ DRMRR 231_ AHSGH 236_ PGSPR 241_ GSLSR 246_ HPSSQ 251_ LAGPG 256_ VEGGE 261_ GTQKP 266_ RDYII 271_ LAILS 276_ CFCPM 281_ WPVNI 286_ VAFAY 291_ AVMSR 296_ NSLQQ 301_ GDVDG 306_ AQRLG 311_ RVAKL 316_ LSIVA 321_ LVGGV 326_ LIIIA 331_SCVIN
1: As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and down-regulate short-term facilitation