Transcription factor AP-2-delta (AP2-delta) (Activating enhancer-binding protein 2-delta) (Transcription factor AP-2-beta-like 1)
1_MSTTF 6_ PGLVH 11_ DAEIR 16_ HDGSN 21_ SYRLM 26_ QLGCL 31_ ESVAN 36_ STVAY 41_ SSSSP 46_ LTYST 51_ TGTEF 56_ ASPYF 61_ STNHQ 66_ YTPLH 71_ HQSFH 76_ YEFQH 81_ SHPAV 86_ TPDAY 91_ SLNSL 96_ HHSQQ 101_ YYQQI 106_ HHGEP 111_ TDFIN 116_ LHNAR 121_ ALKSS 126_ CLDEQ 131_ RRELG 136_ CLDAY 141_ RRHDL 146_ SLMSH 151_ GSQYG 156_ MHPDQ 161_ RLLPG 166_ PSLGL 171_ AAAGA 176_ DDLQG 181_ SVEAQ 186_ CGLVL 191_ NGQGG 196_ VIRRG 201_ GTCVV 206_ NPTDL 211_ FCSVP 216_ GRLSL 221_ LSSTS 226_ KYKVT 231_ IAEVK 236_ RRLSP 241_ PECLN 246_ ASLLG 251_ GILRR 256_ AKSKN 261_ GGRCL 266_ REKLD 271_ RLGLN 276_ LPAGR 281_ RKAAN 286_ VTLLT 291_ SLVEG 296_ EALHL 301_ ARDFG 306_ YTCET 311_ EFPAK 316_ AVGEH 321_ LARQH 326_ MEQKE 331_ QTARK 336_ KMILA 341_ TKQIC 346_ KEFQD 351_ LLSQD 356_ RSPLG 361_ SSRPT 366_ PILDL 371_ DIQRH 376_ LTHFS 381_ LITHG 386_ FGTPA 391_ ICAAL 396_ STFQT 401_ VLSEM 406_ LNYLE 411_ KHTTH 416_ KNGGA 421_ ADSGQ 426_ GHANS 431_ EKAPL 436_ RKTSE 441_ AAVKE 446_GKTEK
1: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity)