Complexin-4 (Complexin IV) (CPX IV)
1_MAFLM 6_ KSMIS 11_ NQVKN 16_ LGFGG 21_ GSEEN 26_ KEEGG 31_ ASDPA 36_ AAQGM 41_ TREEY 46_ EEYQK 51_ QMIEE 56_ KMERD 61_ AAFTQ 66_ KKAER 71_ ACLRV 76_ HLREK 81_ YRLPK 86_ SEMDE 91_ NQIQM 96_ AGDDV 101_ DLPED 106_ LRKMV 111_ DEDQE 116_ EEEDK 121_ DSILG 126_ QIQNL 131_ QNMDL 136_ DTIKE 141_ KAQAT 146_ FTEIK 151_QTAEQ
1: Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity)