Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (GMP25iso) (Putative NF-kappa-B-activating protein 156) (p24 family protein alpha-3) (p24alpha3)
1_MAGVG 6_ AGPLR 11_ AMGRQ 16_ ALLLL 21_ ALCAT 26_ GAQGL 31_ YFHIG 36_ ETEKR 41_ CFIEE 46_ IPDET 51_ MVIGN 56_ YRTQM 61_ WDKQK 66_ EVFLP 71_ STPGL 76_ GMHVE 81_ VKDPD 86_ GKVVL 91_ SRQYG 96_ SEGRF 101_ TFTSH 106_ TPGDH 111_ QICLH 116_ SNSTR 121_ MALFA 126_ GGKLR 131_ VHLDI 136_ QVGEH 141_ ANNYP 146_ EIAAK 151_ DKLTE 156_ LQLRA 161_ RQLLD 166_ QVEQI 171_ QKEQD 176_ YQRYR 181_ EERFR 186_ LTSES 191_ TNQRV 196_ LWWSI 201_ AQTVI 206_ LILTG 211_ IWQMR 216_ HLKSF 221_FEAKK
1: Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity)