Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA)
1_MSLRV 6_ HTLPT 11_ LLGAV 16_ VRPGC 21_ RELLC 26_ LLMIT 31_ VTVGP 36_ GASGV 41_ CPTAC 46_ ICATD 51_ IVSCT 56_ NKNLS 61_ KVPGN 66_ LFRLI 71_ KRLDL 76_ SYNRI 81_ GLLDS 86_ EWIPV 91_ SFAKL 96_ NTLIL 101_ RHNNI 106_ TSIST 111_ GSFST 116_ TPNLK 121_ CLDLS 126_ SNKLK 131_ TVKNA 136_ VFQEL 141_ KVLEV 146_ LLLYN 151_ NHISY 156_ LDPSA 161_ FGGLS 166_ QLQKL 171_ YLSGN 176_ FLTQF 181_ PMDLY 186_ VGRFK 191_ LAELM 196_ FLDVS 201_ YNRIP 206_ SMPMH 211_ HINLV 216_ PGKQL 221_ RGIYL 226_ HGNPF 231_ VCDCS 236_ LYSLL 241_ VFWYR 246_ RHFSS 251_ VMDFK 256_ NDYTC 261_ RLWSD 266_ SRHSR 271_ QVLLL 276_ QDSFM 281_ NCSDS 286_ IINGS 291_ FRALG 296_ FIHEA 301_ QVGER 306_ LMVHC 311_ DSKTG 316_ NANTD 321_ FIWVG 326_ PDNRL 331_ LEPDK 336_ EMENF 341_ YVFHN 346_ GSLVI 351_ ESPRF 356_ EDAGV 361_ YSCIA 366_ MNKQR 371_ LLNET 376_ VDVTI 381_ NVSNF 386_ TVSRS 391_ HAHEA 396_ FNTAF 401_ TTLAA 406_ CVASI 411_ VLVLL 416_ YLYLT 421_ PCPCK 426_ CKTKR 431_ QKNML 436_ HQSNA 441_ HSSIL 446_ SPGPA 451_ SDASA 456_ DERKA 461_ GAGKR 466_ VVFLE 471_ PLKDT 476_ AAGQN 481_ GKVRL 486_ FPSEA 491_ VIAEG 496_ ILKST 501_ RGKSD 506_ SDSVN 511_ SVFSD 516_TPFVA
1: Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas