Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP)
1_MAKSP 6_ ENSTL 11_ EEILG 16_ QYQRS 21_ LREHA 26_ SRSIH 31_ QLTCA 36_ LKEGD 41_ VTIGE 46_ DAPNL 51_ SFSTS 56_ VGNED 61_ ARTAW 66_ PELQQ 71_ SHAVN 76_ QLKDL 81_ LRQQA 86_ DKESE 91_ VSPSR 96_ RRKMS 101_ PLRSL 106_ EHEET 111_ NMPTM 116_ HDLVH 121_ TINDQ 126_ SQYIH 131_ HLEAE 136_ VKFCK 141_ EELSG 146_ MKNKI 151_ QVVVL 156_ ENEGL 161_ QQQLK 166_ SQRQE 171_ ETLRE 176_ QTLLD 181_ ASGNM 186_ HNSWI 191_ TTGED 196_ SGVGE 201_ TSKRP 206_ FSHDN 211_ ADFGK 216_ AASAG 221_ EQLEL 226_ EKLKL 231_ TYEEK 236_ CEIEE 241_ SQLKF 246_ LRNDL 251_ AEYQR 256_ TCEDL 261_ KEQLK 266_ HKEFL 271_ LAANT 276_ CNRVG 281_ GLCLK 286_ CAQHE 291_ AVLSQ 296_ THTNV 301_ HMQTI 306_ ERLVK 311_ ERDDL 316_ MSALV 321_ SVRSS 326_ LADTQ 331_ QREAS 336_ AYEQV 341_ KQVLQ 346_ ISEEA 351_ NFEKT 356_ KALIQ 361_ CDQLR 366_ KELER 371_ QAERL 376_ EKELA 381_ SQQEK 386_ RAIEK 391_ DMMKK 396_ EITKE 401_ REYMG 406_ SKMLI 411_ LSQNI 416_ AQLEA 421_ QVEKV 426_ TKEKI 431_ SAINQ 436_ LEEIQ 441_ SQLAS 446_ REMDV 451_ TKVCG 456_ EMRYQ 461_ LNKTN 466_ MEKDE 471_ AEKEH 476_ REFRA 481_ KTNRD 486_ LEIKD 491_ QEIEK 496_ LRIEL 501_ DESKQ 506_ HLEQE 511_ QQKAA 516_ LAREE 521_ CLRLT 526_ ELLGE 531_ SEHQL 536_ HLTRQ 541_ EKDSI 546_ QQSFS 551_ KEAKA 556_ QALQA 561_ QQREQ 566_ ELTQK 571_ IQQME 576_ AQHDK 581_ TENEQ 586_ YLLLT 591_ SQNTF 596_ LTKLK 601_ EECCT 606_ LAKKL 611_ EQISQ 616_ KTRSE 621_ IAQLS 626_ QEKRY 631_ TYDKL 636_ GKLQR 641_ RNEEL 646_ EEQCV 651_ QHGRV 656_ HETMK 661_ QRLRQ 666_ LDKHS 671_ QATAQ 676_ QLVQL 681_ LSKQN 686_ QLLLE 691_ RQSLS 696_ EEVDR 701_ LRTQL 706_PSMPQ
1: Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis (PubMed:27224062)