Gene name: MARCHF3

Uniprot entry:

Q86UD3

Protein names:

E3 ubiquitin-protein ligase MARCHF3 (EC 2.3.2.27) (Membrane-associated RING finger protein 3) (Membrane-associated RING-CH protein III) (MARCH-III) (RING finger protein 173) (RING-type E3 ubiquitin transferase MARCHF3)

Protein sequence:

1_MTTSR 6_ CSHLP 11_ EVLPD 16_ CTSSA 21_ APVVK 26_ TVEDC 31_ GSLVN 36_ GQPQY 41_ VMQVS 46_ AKDGQ 51_ LLSTV 56_ VRTLA 61_ TQSPF 66_ NDRPM 71_ CRICH 76_ EGSSQ 81_ EDLLS 86_ PCECT 91_ GTLGT 96_ IHRSC 101_ LEHWL 106_ SSSNT 111_ SYCEL 116_ CHFRF 121_ AVERK 126_ PRPLV 131_ EWLRN 136_ PGPQH 141_ EKRTL 146_ FGDMV 151_ CFLFI 156_ TPLAT 161_ ISGWL 166_ CLRGA 171_ VDHLH 176_ FSSRL 181_ EAVGL 186_ IALTV 191_ ALFTI 196_ YLFWT 201_ LVSFR 206_ YHCRL 211_ YNEWR 216_ RTNQR 221_ VILLI 226_ PKSVN 231_ VPSNQ 236_ PSLLG 241_ LHSVK 246_RNSKE

Protein annotations

Protein functions:

1: E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates