Adiponectin receptor protein 2 (Progestin and adipoQ receptor family member 2) (Progestin and adipoQ receptor family member II)
1_MNEPT 6_ ENRLG 11_ CSRTP 16_ EPDIR 21_ LRKGH 26_ QLDGT 31_ RRGDN 36_ DSHQG 41_ DLEPI 46_ LEASV 51_ LSSHH 56_ KKSSE 61_ EHEYS 66_ DEAPQ 71_ EDEGF 76_ MGMSP 81_ LLQAH 86_ HAMEK 91_ MEEFV 96_ CKVWE 101_ GRWRV 106_ IPHDV 111_ LPDWL 116_ KDNDF 121_ LLHGH 126_ RPPMP 131_ SFRAC 136_ FKSIF 141_ RIHTE 146_ TGNIW 151_ THLLG 156_ CVFFL 161_ CLGIF 166_ YMFRP 171_ NISFV 176_ APLQE 181_ KVVFG 186_ LFFLG 191_ AILCL 196_ SFSWL 201_ FHTVY 206_ CHSEG 211_ VSRLF 216_ SKLDY 221_ SGIAL 226_ LIMGS 231_ FVPWL 236_ YYSFY 241_ CNPQP 246_ CFIYL 251_ IVICV 256_ LGIAA 261_ IIVSQ 266_ WDMFA 271_ TPQYR 276_ GVRAG 281_ VFLGL 286_ GLSGI 291_ IPTLH 296_ YVISE 301_ GFLKA 306_ ATIGQ 311_ IGWLM 316_ LMASL 321_ YITGA 326_ ALYAA 331_ RIPER 336_ FFPGK 341_ CDIWF 346_ HSHQL 351_ FHIFV 356_ VAGAF 361_ VHFHG 366_ VSNLQ 371_ EFRFM 376_ IGGGC 381_SEEDA
1: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity)