2-acylglycerol O-acyltransferase 3 (EC 2.3.1.20) (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 3) (MGAT3) (Diacylglycerol O-acyltransferase candidate 7) (hDC7) (Diacylglycerol acyltransferase 2-like protein 7) (Monoacylglycerol O-acyltransferase 3)
1_MGVAT 6_ TLQPP 11_ TTSKT 16_ LQKQH 21_ LEAVG 26_ AYQYV 31_ LTFLF 36_ MGPFF 41_ SLLVF 46_ VLLFT 51_ SLWPF 56_ SVFYL 61_ VWLYV 66_ DWDTP 71_ NQGGR 76_ RSEWI 81_ RNRAI 86_ WRQLR 91_ DYYPV 96_ KLVKT 101_ AELPP 106_ DRNYV 111_ LGAHP 116_ HGIMC 121_ TGFLC 126_ NFSTE 131_ SNGFS 136_ QLFPG 141_ LRPWL 146_ AVLAG 151_ LFYLP 156_ VYRDY 161_ IMSFG 166_ LCPVS 171_ RQSLD 176_ FILSQ 181_ PQLGQ 186_ AVVIM 191_ VGGAH 196_ EALYS 201_ VPGEH 206_ CLTLQ 211_ KRKGF 216_ VRLAL 221_ RHGAS 226_ LVPVY 231_ SFGEN 236_ DIFRL 241_ KAFAT 246_ GSWQH 251_ WCQLT 256_ FKKLM 261_ GFSPC 266_ IFWGR 271_ GLFSA 276_ TSWGL 281_ LPFAV 286_ PITTV 291_ VGRPI 296_ PVPQR 301_ LHPTE 306_ EEVNH 311_ YHALY 316_ MTALE 321_ QLFEE 326_ HKESC 331_ GVPAS 336_TCLTF
1: Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) (PubMed:28420705)