Testis-specific Y-encoded-like protein 5 (TSPY-like protein 5)
1_MSGRS 6_ RGRKS 11_ SRAKN 16_ RGKGR 21_ AKARV 26_ RPAPD 31_ DAPRD 36_ PDPSQ 41_ YQSLG 46_ EDTQA 51_ AQVQA 56_ GAGWG 61_ GLEAA 66_ ASAQL 71_ LRLGE 76_ EAACR 81_ LPLDC 86_ GLALR 91_ ARAAG 96_ DHGQA 101_ AARPG 106_ PGKAA 111_ SLSER 116_ LAADT 121_ VFVGT 126_ AGTVG 131_ RPKNA 136_ PRVGN 141_ RRGPA 146_ GKKAP 151_ ETCST 156_ AGRGP 161_ QVIAG 166_ GRQKK 171_ GAAGE 176_ NTSVS 181_ AGEEK 186_ KEERD 191_ AGSGP 196_ PATEG 201_ SMDTL 206_ ENVQL 211_ KLENM 216_ NAQAD 221_ RAYLR 226_ LSRKF 231_ GQLRL 236_ QHLER 241_ RNHLI 246_ QNIPG 251_ FWGQA 256_ FQNHP 261_ QLASF 266_ LNSQE 271_ KEVLS 276_ YLNSL 281_ EVEEL 286_ GLARL 291_ GYKIK 296_ FYFDR 301_ NPYFQ 306_ NKVLI 311_ KEYGC 316_ GPSGQ 321_ VVSRS 326_ TPIQW 331_ LPGHD 336_ LQSLS 341_ QGNPE 346_ NNRSF 351_ FGWFS 356_ NHSSI 361_ ESDKI 366_ VEIIN 371_ EELWP 376_ NPLQF 381_ YLLSE 386_ GARVE 391_ KGKEK 396_ EGRQG 401_ PGKQP 406_ METTQ 411_PGVSQ
1: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7