Gene name: PAQR7

Uniprot entry:

Q86WK9

Protein names:

Membrane progestin receptor alpha (mPR alpha) (Membrane progesterone P4 receptor alpha) (Membrane progesterone receptor alpha) (Progesterone and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member VII)

Protein sequence:

1_MAMAQ 6_ KLSHL 11_ LPSLR 16_ QVIQE 21_ PQLSL 26_ QPEPV 31_ FTVDR 36_ AEVPP 41_ LFWKP 46_ YIYAG 51_ YRPLH 56_ QTWRF 61_ YFRTL 66_ FQQHN 71_ EAVNV 76_ WTHLL 81_ AALVL 86_ LLRLA 91_ LFVET 96_ VDFWG 101_ DPHAL 106_ PLFII 111_ VLASF 116_ TYLSF 121_ SALAH 126_ LLQAK 131_ SEFWH 136_ YSFFF 141_ LDYVG 146_ VAVYQ 151_ FGSAL 156_ AHFYY 161_ AIEPA 166_ WHAQV 171_ QAVFL 176_ PMAAF 181_ LAWLS 186_ CIGSC 191_ YNKYI 196_ QKPGL 201_ LGRTC 206_ QEVPS 211_ VLAYA 216_ LDISP 221_ VVHRI 226_ FVSSD 231_ PTTDD 236_ PALLY 241_ HKCQV 246_ VFFLL 251_ AAAFF 256_ STFMP 261_ ERWFP 266_ GSCHV 271_ FGQGH 276_ QLFHI 281_ FLVLC 286_ TLAQL 291_ EAVAL 296_ DYEAR 301_ RPIYE 306_ PLHTH 311_ WPHNF 316_ SGLFL 321_ LTVGS 326_ SILTA 331_ FLLSQ 336_ LVQRK 341_LDQKT

Protein annotations

Protein functions:

1: Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870)