Uncharacterized protein C12orf40
1_MNWVG 6_ GSRSR 11_ VLIKQ 16_ ERRKQ 21_ KEYFE 26_ KHRLK 31_ SKMKS 36_ LGVLS 41_ PVKNS 46_ AVSLD 51_ ILNLY 56_ MVNQI 61_ SCKKK 66_ IPETV 71_ RKPTH 76_ VNMNR 81_ DIKMP 86_ LRKHN 91_ LELTM 96_ SPHCV 101_ PSKLC 106_ LDDTE 111_ TNVNC 116_ QRLSS 121_ KEDLG 126_ PVQSQ 131_ GMDSY 136_ SMLHP 141_ QFSKI 146_ ENCSF 151_ TPSSF 156_ SVELP 161_ SNRHI 166_ SKLNF 171_ TSGIA 176_ PTPQK 181_ LAYEK 186_ KQNDQ 191_ RSTVN 196_ CSDSL 201_ LSKLN 206_ KSQDV 211_ FSPSH 216_ KTTRF 221_ GTLFE 226_ RLNSL 231_ GNRNL 236_ LTKSP 241_ AVIMD 246_ EDCRS 251_ TDEIR 256_ QSDYI 261_ TEKHS 266_ IQHIW 271_ GKNGK 276_ EVSNF 281_ LEDVN 286_ QSTPN 291_ LLSEN 296_ CDSFV 301_ SQNMI 306_ NVLNI 311_ DEQRI 316_ KKTFN 321_ KCDYD 326_ SMGDT 331_ CVVTS 336_ SDKNH 341_ VTDRC 346_ IRNIF 351_ TVPEL 356_ TFSNS 361_ TLNKT 366_ SYPEK 371_ CQPNK 376_ KYQRE 381_ YNKNE 386_ RNDLS 391_ TSFEN 396_ DYYPS 401_ SSERK 406_ EKFEN 411_ DYQEK 416_ TPQKS 421_ IQKYP 426_ ANSMG 431_ NIPSE 436_ ELHSK 441_ QSWDF 446_ GLDEI 451_ LMEEG 456_ GIYSL 461_ KSKRI 466_ STKKI 471_ SLDSA 476_ QSSRS 481_ TSYSP 486_ RPTDS 491_ CFSSS 496_ SDLPS 501_ EDEDQ 506_ ISQQI 511_ EDSNR 516_ MTIKT 521_ KEKMN 526_ NFYVE 531_ RMAKL 536_ SGDRI 541_ VKNDD 546_ KIHKQ 551_ NENFY 556_ QFSVK 561_ NNTDQ 566_ FPQLQ 571_ CNSAH 576_ ILQNK 581_ TNDNC 586_ VLQAA 591_ RCDAG 596_ IQTES 601_ ESVME 606_ EKLDV 611_ AIQCD 616_ LISKC 621_ TCRSD 626_ VSLCN 631_ LERCS 636_ GNIKA 641_ DTTGG 646_QEIHK
1: Involved in recombination, probably acting by stabilizing recombination intermediates during meiotic crossover formation. Required for normal germline development and fertility. Required for meiotic progression, complete chromosomal synapsis and crossover formation. Binds double-stranded DNA. However, also binds branched DNA molecules, such as those containing a D-loop or Holliday junction structure. Probably not required for formation of DNA double-strand breaks (DSBs). Also binds RNA in an RNA structure-independent manner, with a preference for binding 3'-UTR regions of mRNAs; may stabilize bound RNAs