Gene name: SKAP1

Uniprot entry:

Q86WV1

Protein names:

Src kinase-associated phosphoprotein 1 (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55)

Protein sequence:

1_MQAAA 6_ LPEEI 11_ RWLLE 16_ DAEEF 21_ LAEGL 26_ RNENL 31_ SAVAR 36_ DHRDH 41_ ILRGF 46_ QQIKA 51_ RYYWD 56_ FQPQG 61_ GDIGQ 66_ DSSDD 71_ NHSGT 76_ LGLSL 81_ TSDAP 86_ FLSDY 91_ QDEGM 96_ EDIVK 101_ GAQEL 106_ DNVIK 111_ QGYLE 116_ KKSKD 121_ HSFFG 126_ SEWQK 131_ RWCVV 136_ SRGLF 141_ YYYAN 146_ EKSKQ 151_ PKGTF 156_ LIKGY 161_ GVRMA 166_ PHLRR 171_ DSKKE 176_ SCFEL 181_ TSQDR 186_ RSYEF 191_ TATSP 196_ AEARD 201_ WVDQI 206_ SFLLK 211_ DLSSL 216_ TIPYE 221_ EDEEE 226_ EEKEE 231_ TYDDI 236_ DGFDS 241_ PSCGS 246_ QCRPT 251_ ILPGS 256_ VGIKE 261_ PTEEK 266_ EEEDI 271_ YEVLP 276_ DEEHD 281_ LEEDE 286_ SGTRR 291_ KGVDY 296_ ASYYQ 301_ GLWDC 306_ HGDQP 311_ DELSF 316_ QRGDL 321_ IRILS 326_ KEYNM 331_ YGWWV 336_ GELNS 341_ LVGIV 346_ PKEYL 351_TTAFE

Protein annotations

Protein functions:

1: Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells